Prognostic and predictive factors for clinical and radiographic responses in patients with painful bone metastasis treated with magnetic resonance-guided focused ultrasound surgery.

Prognostic and predictive factors for clinical and radiographic responses in patients with painful bone metastasis treated with magnetic resonance-guided focused ultrasound surgery. Int J Hyperthermia. 2019;36(1):932-937 Authors: Tsai YC, Lee HL, Kuo CC, Chen CY, Hsieh KL, Wu MH, Wen YC, Yu HW, Hsu FC, Tsai JT, Chiou JF Abstract Background: Magnetic resonance-guided focused ultrasound surgery (MRgFUS) is an alternative local therapy for patients with painful bone metastasis. However, little is known about the prognostic and predictive factors of MRgFUS in treating bone metastasis. Materials and methods: This retrospective study analyzed the performance status, treated site, pretreatment pain score, pretreatment tumor volume and lesion coverage volume factor (CVF) of 31 patients who underwent MRgFUS. A numerical rating scale for pain was used at the same time to assess the clinical response. Radiographic responses were evaluated using a modified version of The University of Texas MD Anderson Cancer Center criteria and reference to the MR imaging or computed tomography scans obtained 3 months after treatment. Univariate and multivariate logistic regression analyses were conducted to examine the effect of variables on clinical and radiographic responses. Results: The overall clinical response rate was 83.9% and radiographic response rate was 67.7%. Multivariate logistic regression analysis revealed that the better pretreatment Karnofsky performance st...
Source: International Journal of Hyperthermia - Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research

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Conditions:   Anesthesia;   Analgesia;   Acute Pain;   Chronic Pain;   Pectoralis Nerve Block;   Erector Spine Plane Block;   Patient Controlled Analgesia Interventions:   Procedure: Pectoralis nerve block;   Procedure: Erector spine plane block;   Other: Control Sponsors:   Ondokuz Mayıs University;   CENGİZ KAYA (ckaya) Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Chemotherapy-Induced Peripheral Neuropathy;   Malignant Neoplasm Interventions:   Other: Quality-of-Life Assessment;   Other: Questionnaire Administration;   Procedure: Transcranial Direct Current Stimulation Sponsors:   M.D. Anderson Cancer Center;   National Cancer Institute (NCI) Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Whether or not to circumcise your baby is a personal decision often determined by a variety of social, cultural, medical, or religious circumstances. Parents have the right to choose what they believe is best for their newborn and typically undergo extensive research before deciding what’s best for their family. So, what is the process of circumcision? Once parents decide to move forward, about an hour before the procedure, doctors use an anesthetic to numb the baby’s penis. The area is then sterilized and the excess skin on the penis is clamped and cut. Finally, the physician covers the penis in bandages or ga...
Source: Cord Blood News - Category: Perinatology & Neonatology Authors: Tags: babies pregnancy Source Type: blogs
Cancer therapy-induced cognitive impairment adversely affects the quality of life of patients with cancer but cannot be detected by neuropsychological tests.
Source: Journal of Pain and Symptom Management - Category: Palliative Care Authors: Tags: Brief Methodological Report Source Type: research
ConclusionIORT boost appears to be a  highly efficient and safe method for upfront delivery of the tumor bed boost in high-risk breast cancer patients.
Source: Strahlentherapie und Onkologie - Category: Cancer & Oncology Source Type: research
ConclusionLess invasive approaches (mini-open retropleural/retroperitoneal and thoracoscopic) not only had superior outcome in terms of blood loss and operating time, but also were shown to be safe techniques in cancer patients with low rates of procedure-related complications.Graphic abstractThese slides can be retrieved under Electronic Supplementary Material.
Source: European Spine Journal - Category: Orthopaedics Source Type: research
Publication date: Available online 20 October 2019Source: The LancetAuthor(s): Daniel I Sessler, Lijian Pei, Yuguang Huang, Edith Fleischmann, Peter Marhofer, Andrea Kurz, Douglas B Mayers, Tanja A Meyer-Treschan, Martin Grady, Ern Yu Tan, Sabry Ayad, Edward J Mascha, Donal J Buggy, Gang Tan, Zhiyong Zhang, Helen Keane, Maurice Stokes, Oliver Zotti, Michael Gnant, Silvia Perez-ProttoSummaryBackgroundThree perioperative factors impair host defence against recurrence during cancer surgery: the surgical stress response, use of volatile anaesthetic, and opioids for analgesia. All factors are ameliorated by regional anaesthesia...
Source: The Lancet - Category: General Medicine Source Type: research
AbstractPurposeThe oldest old, described as those aged 85 and older, is a growing cancer population. There are limited studies evaluating the symptoms of the oldest old cancer patient population. Our study aimed to evaluate symptom frequency and clinical symptom change as assessed by the Edmonton Symptom Assessment System (ESAS) of the oldest old ( ≥ 85) compared to older adult (65–84) and general adult (18–64) outpatient cancer patients on initial consult and follow-up visit.MethodsRetrospective review of a total of 441 patients, 200 randomly sampled patients in the general and older adult group and ...
Source: Supportive Care in Cancer - Category: Cancer & Oncology Source Type: research
This article aims to evaluate the effectiveness, security, and performance difficulty of GIB in patients with pelvic and perineal oncological pain.MethodsA retrospective study between January 2016 and August 2017. Patients with poorly controlled pelvic oncological pain and patients experimenting opioid side effects in which GIB was performed ambulatory were included. Prognostic GIB was performed, under echographic and fluoroscopic control, with local anesthetic and corticoid. The neurolytic block was performed under fluoroscopic guidance. The technique was performed by the same anesthetist with pain management competence. ...
Source: Supportive Care in Cancer - Category: Cancer & Oncology Source Type: research
ConclusionESWT is a safe and relevant modality for the supportive care and rehabilitation of cancer patients.
Source: Supportive Care in Cancer - Category: Cancer & Oncology Source Type: research
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