The effect of pulse methylprednisolone induction therapy in Chinese patients with dialysis-dependent MPO-ANCA associated vasculitis.

CONCLUSIONS: This retrospective study of MPO-AAV patients who required dialysis at presentation in a single Chinese center suggests that the addition of pulse MP to standard immunosuppressive induction therapy for remission appears to confer no benefit in terms of improving patient outcomes. Further research is required to determine the role of pulse MP in severe MPO-AAV.
PMID: 31536905 [PubMed - as supplied by publisher]

Source: International Immunopharmacology - September 15, 2019 Category: Allergy & Immunology Authors: Huang L, Zhong Y, Ooi JD, Zhou YO, Zuo X, Luo H, Chen JB, Wu T, Yang Y, Meng T, Xiao Z, Lin W, Ao X, Xiao X, Zhou Q, Xiao P Tags: Int Immunopharmacol Source Type: research