The Effect of Hypnotics on Sleep Quality and Cognitive Function in Patients with Brain Tumors.

Conclusion: Quality of sleep in patients with insomnia following brain tumor resection was initially poor but improved significantly after taking hypnotic medication. Further, the hypnotic medications appeared to contribute to the amelioration of cognitive impairments and depressive moods in patients who previously underwent brain tumor resection. We thus recommend the use of hypnotics for patients with brain tumors with insomnia. PMID: 31533416 [PubMed - as supplied by publisher]
Source: Journal of Korean Neurosurgical Society - Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

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Publication date: Available online 18 October 2019Source: IJC Heart &VasculatureAuthor(s): Dominik Linz, Mathias Baumert, Lien Desteghe, Kadhim Kadhim, Kevin Vernooy, Jonathan M. Kalman, Dobromir Dobrev, Michael Arzt, Manu Sastry, Harry J.G.M. Crijns, Ulrich Schotten, Martin R. Cowie, R. Doug McEvoy, Hein Heidbuchel, Jeroen Hendriks, Prashanthan Sanders, Dennis H. LauAbstractIn patients with atrial fibrillation (AF), the prevalence of moderate-to-severe sleep-disordered breathing (SDB) ranges between 21% and 72% and observational studies have demonstrated that SDB reduces the efficacy of rhythm control strategies, whil...
Source: IJC Heart and Vasculature - Category: Cardiology Source Type: research
ConclusionsThe phantom data show the validity of our fast distortion correction algorithm. Patient-specific data are acquired in
Source: Reports of Practical Oncology and Radiotherapy - Category: Cancer & Oncology Source Type: research
In this study, LC/NE neurons were pre-lesioned by N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine (DSP-4) in paraquat and maneb-induced mouse PD model. We found that DSP-4 significantly impaired learning and memory performance in paraquat and maneb-treated mice, although it failed to interfere with constipation and depression-like behaviors. Consistently, DSP-4 treatment increased hippocampal neurodegeneration, synaptic loss, α-synuclein expression and Ser129-phosphorylation in mice treated with these two pesticides. Mechanistically, DSP-4 increased iron content in hippocampus by disrupting the balance of iron release p...
Source: Neuroscience - Category: Neuroscience Source Type: research
Publication date: November 2019Source: Infant Behavior and Development, Volume 57Author(s): Stephanie H. Parade, Kristyn Wong, Renee Belair, Susan Dickstein, Ronald SeiferAbstractObserved infant temperamental difficulty and infant sleep efficiency and sleep variability were examined as predictors of maternal depressive symptoms, maternal sensitivity, and family functioning. Eight observations at 8-months postpartum were used to assess infant temperament, and actigraphy was used to measure infant sleep for 1-week at the time of the 8-month assessment. Structured clinical interviews were used to assess maternal depressive sy...
Source: Infant Behavior and Development - Category: Child Development Source Type: research
This study aims to investigate genetic alterations within EEF1A1, EEF1A2, EEF1B2, EEF1D, EEF1E1 and EEF1G genes and their potential effects on epigenetic regulation mechanisms.Materials and methodsIn this study, we analyzed DNA sequencing and mRNA expression data available on The Cancer Genome Atlas (TCGA) across different cancer types to detect genetic alterations in EEF1 genes and investigated their potential impact on selected epigenetic modulators.Key findingsWe found that EEF1 complex proteins were deregulated in several types of cancer. Lower EEF1A1, EEF1B2, EEF1D and EEF1G levels were correlated with poor survival i...
Source: Life Sciences - Category: Biology Source Type: research
Authors: Lurie I, Barnea Y, Caspi Y, Olmer L, Baruch Y Abstract Aim: Migrants have increased risk for psychiatric hospitalizations. Over the last decades Israel has become a destination for migration of migrant workers and asylum-seekers. Methods: The current retrospective study retrieved socio-demographic, clinical and migration-related chart data for 117 migrants admitted to a major Israeli psychiatric hospital between 2005-2011, to delineate characteristics and risk-factors for psychiatric hospitalizations. Multivariate logistic regression analyses were performed to predict re-hospitalization. Results: Of the st...
Source: Nordic Journal of Psychiatry - Category: Psychiatry Tags: Nord J Psychiatry Source Type: research
Publication date: 19 October 2019Source: New Scientist, Volume 244, Issue 3252Author(s): Jessica Hamzelou
Source: New Scientist - Category: Science Source Type: research
Authors: Sano M, Kaneko MK, Kato Y Abstract The highly O-glycosylated membrane glycoprotein podoplanin (PDPN) is frequently overexpressed in several malignant cancers, such as oral cancer, lung cancer, germinal neoplasia, mesothelioma, and brain tumor. The expression of PDPN is strongly associated with cancer progression and poor prognosis. PDPN possesses three tandem repeats of platelet aggregation-stimulating (PLAG) domains (PLAG1, PLAG2, and PLAG3) and PLAG-like domain (PLD), and binds to C-type lectin-like receptor 2 (CLEC-2) on platelets, followed by PDPN-mediated platelet aggregation. We have previously estab...
Source: Monoclonal Antibodies in Immunodiagnosis and Immunotherapy - Category: Microbiology Tags: Monoclon Antib Immunodiagn Immunother Source Type: research
Publication date: Available online 18 October 2019Source: Revista Clínica Española (English Edition)Author(s): M. Baeza, A. Muñoz-Ortega, N. VelaAbstractObjectiveTo assess the characteristics of acute poisoning cases treated in hospital emergency departments over 5 years.MethodsRetrospective study of acute poisoning cases treated in 3 hospitals between 2013 and 2017 and an analysis of the demographic characteristics, types of poisoning, seasonal variations, care received and recurrence.ResultsSome 0.51% of all cases treated in the 3 hospitals corresponded to acute poisoning. The percentages varied by h...
Source: Revista Clinica Espanola - Category: Internal Medicine Source Type: research
GR Abstract OBJECTIVES: To examine the effect of informal cancer caregiving and repetitive negative thinking (RNT) on depressive symptoms and salivary cortisol levels. SAMPLE & SETTING: The sample was recruited from a hospital bone marrow unit and caregiver support organizations. It included 60 informal cancer caregivers (52% partners) of individuals with cancer who provided care for a median of 27.5 hours per week for 12 months, and 46 noncaregiver participants. METHODS & VARIABLES: In this cross-sectional study, participants completed questionnaires assessing RNT and depressive symptoms and pr...
Source: Oncology Nursing Forum - Category: Nursing Authors: Tags: Oncol Nurs Forum Source Type: research
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