Invasion of primary glioma- and cell line-derived spheroids implanted into corticostriatal slice cultures.

In conclusion, the invasion of gliomas is preserved using primary glioma spheroids. Some stem cell features are preserved as well, making this model useful in drug development elucidating both invasion and cancer stemness at the early in vitro level. PMID: 23573302 [PubMed - in process]

http://www.ncbi.nlm.nih.gov/pubmed/23573302?dopt=Abstract

Source: International Journal of Clinical and Experimental Pathology - May 26, 2013 Category: Pathology Authors: Aaberg-Jessen C, Nørregaard A, Christensen K, Pedersen CB, Andersen C, Kristensen BW Tags: Int J Clin Exp Pathol Source Type: research