Inhibitory effect of bone morphogenetic protein-7 on hepatic fibrosis in rats.

CONCLUSIONS: BMP-7 can attenuate and even prevent the level of hepatic fibrosis in rats through inhibiting the expression of TGF-β1 in the liver fibrotic tissues. Therefore, it may be a potential clinical drug for the prevention and treatment of hepatic fibrosis.
PMID: 23638221 [PubMed - in process]

Source: International Journal of Clinical and Experimental Pathology - May 26, 2013 Category: Pathology Authors: Wang SL, Yang CQ, Qi XL, Yuan M, Chang YZ, Yang L, Gao HJ Tags: Int J Clin Exp Pathol Source Type: research