Electrochemotherapy and Ablative Therapies in Non-melanoma Skin Cancer

Although surgery and radiotherapy remain the most commonly used treatments for non-melanoma skin cancer, there are a variety of alternatives. Here we discuss the use of electrochemotherapy and ablative treatments and examine the evidence for their effectiveness against a number of non-melanoma skin cancers.
Source: Clinical Oncology - Category: Radiology Authors: Tags: Overview Source Type: research

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This study does not provide evidence for an increased skin cancer risk in patients treated with NB-UVB phototherapy. However, we have detected the occurence of 10 cases of solar lentigines. Still, definitive prospective longitudinal studies with a greater number of patients and prolonged follow-up are required to specifically address skin cancer risk in relation to NB-UVB phototherapy.
Source: Archives of Dermatological Research - Category: Dermatology Source Type: research
Malignant mesothelioma has become the latest deadly cancer linked directly to the rescue, recovery and cleanup efforts following the 9/11 terrorist attack on New York City in 2001. The long-running threat has come to fruition. Eighteen years after Manhattan was engulfed in the asbestos-laced, toxic cloud of dust — caused primarily by the World Trade Center destruction — the first death from pleural mesothelioma attributed to 9/11 has been recorded. Nick Ursta, 52, from the southwestern part of Pennsylvania, died after a year-long battle with the rare cancer. Ursta, a construction worker and fireman by trade, w...
Source: Asbestos and Mesothelioma News - Category: Environmental Health Authors: Source Type: news
ConclusionsIn patients with RA, the relative increase in etanercept-associated risk of experiencing congestive heart failure, serious infection, non-melanoma skin cancer, or interstitial lung disease was similar between elderly and non-elderly.
Source: Drugs and Aging - Category: Geriatrics Source Type: research
In the last two decades, the U.S. has seen a dramatic rise in the rates of both melanoma and non-melanoma skin cancers, which are linked to ultraviolet radiation exposure.1 Non-melanoma skin cancer, which include basal cell carcinoma and squamous cell carcinoma, are the most common malignancies in the U.S.. Melanoma is the fifth most common cancer, and it has been projected that nearly 100,000 new cases of melanoma will be diagnosed in this country by the end of 2019.2
Source: The American Journal of Medicine - Category: General Medicine Authors: Tags: Review Source Type: research
The current literature is limited with regards to trends for inpatient head and neck skin cancer reconstruction. Rather, studies have focused primarily on patients treated on an outpatient basis. To gain a better understanding of the effect that reconstructive correction of complex skin cancer defects has on the healthcare system, we examined the existing incidence and reconstructive trends of head and neck melanoma and non-melanoma skin cancer (NMSC) in the inpatient setting.
Source: Journal of Plastic, Reconstructive and Aesthetic Surgery - Category: Cosmetic Surgery Authors: Source Type: research
ConclusionsThe use of NSAIDs might reduce the risk of SC, but many factors including study population, drug subtype, and disease subclass affect the significance of the association.Graphical abstract
Source: Pharmacological Research - Category: Drugs & Pharmacology Source Type: research
Lung cancer is the most common cancer in Canada, excluding non-melanoma skin cancers, with an estimated 29,300 new cases in 2019 [1]. It is the leading cause of cancer-related mortality in Canada, accounting for approximately 26% of all cancer-related deaths [1]. Non-small cell lung cancer (NSCLC) is the most common form, representing approximately 80-85% of all lung cancers [2]. Approximately 50% of NSCLC patients are diagnosed at an advanced stage [3]. The prognosis for patients with advanced NSCLC (aNSCLC) remains poor, with a 5-year survival rate ranging from 2-13% [4 –7].
Source: Lung Cancer - Category: Cancer & Oncology Authors: Source Type: research
AbstractThere is a pressing need for monitoring cancerous tissue response to laser therapy. In this work, we evaluate the viability of elastic scattering spectroscopy  (ESS) to monitor malignant transformations and effects of laser therapy of induced skin cancer in a hamster model. Skin tumors were induced in 35 mice, half of which were irradiated with 980 nm laser diode. Physiological and morphological transformations in the tumor were monitored over a period o f 36 weeks using elastic scattering spectroscopy, in the near infrared window. Analytical model for light scattering was used to derive scattering optical pro...
Source: Lasers in Medical Science - Category: Laser Surgery Source Type: research
In this report, we analyzed gene expression profiles of paired specimens of keratinocyte carcinomas with their matched normal skin tissues as the control. Among several novel findings, we discovered a significant number of zinc finger encoding genes up-regulated in human BCC. In BCC, a novel link was found between hedgehog signaling, Wnt signaling, and the cilium. While the SCC cancer-stem-cell gene signature is shared between human and mouse SCCs, the hair follicle stem-cell signature of mice was not highly represented in human SCC. Differential gene expression (DEG) in human BCC shares gene signature with both bulge and ...
Source: Genes and Diseases - Category: Genetics & Stem Cells Source Type: research
Why are geriatric patients less likely to get treated for their non-melanoma skin cancers? Researchers investigate and report.  
Source: CancerNetwork - Category: Cancer & Oncology Authors: Source Type: news
More News: Cancer | Cancer & Oncology | Melanoma | Nonmelanoma Skin Cancer | Radiology | Skin | Skin Cancer