GSE137747 RNA sequencing revealed nasal epithelium-initiated pathways contributing to influenza damage and complications

Contributor : Anand Kumar AndiappanSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensRNA sequencig study for influenza response
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research

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Publication date: Available online 15 October 2019Source: IDCasesAuthor(s): Garyfallia Syridou, Ioannis Drikos, Artemis Vintila, Antigoni Pegkou, Loukia Zografou, Panagiotis Roungas, Eleni Papa, Dimitris Kyriazopoulos, Olga Savelieva, Antonopoulou EleniAbstractInfluenza virus primarily affects the respiratory system. It rarely causes extrapulmonary complications, with otitis media and febrile seizures being the most common in children. Acute glomerulonephritis as a complication of H1N1 influenza virus infection has been described only sporadically.Herein we present a case of acute glomerulonephritis in a previously healthy...
Source: IDCases - Category: Infectious Diseases Source Type: research
Publication date: Available online 15 October 2019Source: Pharmacology &TherapeuticsAuthor(s): Edward D. Chan, Michael M. Chan, Mallory M. Chan, Paul E. MarikAbstractGlucocorticoids (GC) in all its various forms and formulations are likely one of the most commonly used pharmacologic agents in medicine. Their use can be profoundly therapeutic but are also associated with a myriad of acute and chronic side effects. It is fairly well-accepted in the medical community that GC can be life-saving when used in critically ill patients with severe exacerbations of asthma and chronic obstructive pulmonary disease, HIV-associated...
Source: Pharmacology and Therapeutics - Category: Drugs & Pharmacology Source Type: research
According to recent research from the CDC, about 65% of mothers surveyed reported they had not received the seasonal influenza and tetanus, diphtheria and acellular pertussis vaccines before or during pregnancy.
Source: AAFP News - Category: Primary Care Source Type: news
This paper describes the implementation of an influenza vaccine screening and administration process to improve influenza vaccination rates among pediatric hematology and oncology inpatients.Pediatric Nursing
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Pediatrics Journal Article Source Type: news
K. E. Lafond et al.
Source: Emerging Infectious Diseases Journal - Category: Infectious Diseases Source Type: research
Nature, Published online: 16 October 2019; doi:10.1038/d41586-019-03072-8The technology could help to boost immunity against cancer, influenza and much more.
Source: Nature AOP - Category: Research Authors: Source Type: research
Future Virology, Ahead of Print.
Source: Future Virology - Category: Virology Authors: Source Type: research
AbstractInfluenza A virus (IAV) infection is perennially one of the leading causes of death worldwide. Effective therapy and vaccination are needed to control viral expansion. However, current anti-IAV drugs risk inducing drug-resistant virus emergence. Although intranasal administration of whole inactivated virus vaccine can induce efficient protective immunity, formalin and β-propiolactone are the currently used and harmful inactivating agents. Here, we analyzed the antiviral activity of hibiscus (Hibiscus sabdariffa L.) tea extract against human IAV and evaluated its potential as a novel anti-IAV drug and a safe in...
Source: Food and Environmental Virology - Category: Virology Source Type: research
This study suggests that photodynamic treatment can be used to manufacture “bald” virions for experimental purposes. Photodynamic inactivation is based on the production of reactive oxygen species which attack and destroy biomolecules. Thus, the results of this study can potentially apply to other enveloped viruses and sources of singlet oxygen.
Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research
Hantaviruses, etiologic pathogens responsible for two severe human diseases, exist in areas ranging from Eurasia to America and remain global public health concerns. Conventionally, plaque formation assays have been used for hantavirus titering. However, hantaviruses replicate slowly within cells and produce minimal cytopathic effects, making this technique difficult to master. The improved enzyme-linked immunosorbent assay-based antigen detection method is easier to perform but is still time consuming. Here, we established an enzyme-linked focus formation assay (FFA) for Hantaan virus titering that is twice as fast as tra...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
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