Selective Inhibitors of Nuclear Export in the Treatment of Hematologic Malignancies

We report results of preclinical studies and clinical trials, and discuss the mechanism of action of SINEs and their effects in multiple myeloma, non-Hodgkin lymphomas, lymphoblastic leukemia, and acute and chronic myeloid leukemia.

Source: Clinical Lymphoma, Myeloma and Leukemia - August 28, 2019 Category: Hematology Authors: Alessandro Allegra, Vanessa Innao, Andrea Gaetano Allegra, Rossana Leanza, Caterina Musolino Tags: Review Source Type: research