Angiotensin-(1-7) for diabetic kidney disease: better than an angiotensin-converting enzyme inhibitor alone?

In this commentary we emphasize the renoprotective effect of cyclic  angiotensin-(1-7) described by Cassis et al. in a mouse model of diabetic kidney disease. The importance of the study is that this peptide was even more protective than the angiotensin-converting enzyme inhibitor lisinopril administered alone and that when the 2 componds were combined, the ren oprotective action was additive.
Source: Kidney International - Category: Urology & Nephrology Authors: Tags: Commentary Source Type: research