Patients with Musculoskeletal Dysplasia Undergoing Total Joint Arthroplasty are at Increased Risk of Surgical Site Infection

Publication date: Available online 18 September 2019Source: Orthopaedics &Traumatology: Surgery &ResearchAuthor(s): Harshadkumar Patel, Kyle H. Cichos, Andrew S. Moon, Gerald McGwin, Brent A. Ponce, Elie S. GhanemAbstractIntroductionMusculoskeletal dysplasias (MSD) are inherited conditions of abnormal cartilage and bone development and remodeling which include, amongst others, multiple epiphyseal dysplasia (MED), spondyloepiphyseal dysplasia (SED), achondroplasia, and hypochondroplasia. The aim of this study was to compare patient characteristics and in-hospital complications between MSD and non-MSD patients undergoing total joint arthroplasty (TJA).HypothesisMSD patients undergoing TJA are at increased risk of in-hospital post-operative complications and mortality compared to non-MSD patients.Materials and methodsThe Nationwide Inpatient Sample (NIS) from the years 2005 to 2014 was used for this retrospective cohort study. International Classification of Diseases, Clinical Modifications (ICD-9-CM) procedure codes identified primary total knee arthroplasty (TKA) and total hip arthroplasty (THA) procedures and were used to separate MSD and non-MSD patients. Patients with trauma or malignancy as primary diagnoses, non-elective procedures, revision procedures, and concurrent bilateral surgeries were excluded. Patients were compared using linear regression or multivariate logistic regression analysis to control for confounders. All statistical analyses were performed taki...
Source: Orthopaedics and Traumatology: Surgery and Research - Category: Orthopaedics Source Type: research

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