Eosinophilic esophagitis: Current concepts in diagnosis and treatment.

Eosinophilic esophagitis: Current concepts in diagnosis and treatment. World J Gastroenterol. 2019 Aug 28;25(32):4598-4613 Authors: Gómez-Aldana A, Jaramillo-Santos M, Delgado A, Jaramillo C, Lúquez-Mindiola A Abstract Eosinophilic esophagitis is an immune-allergic pathology of multifactorial etiology (genetic and environmental) that affects both pediatric and adult patients. Its symptoms, which include heartburn, regurgitation, and esophageal stenosis (with dysphagia being more frequent in eosinophilic esophagitis in young adults and children), are similar to those of gastroesophageal reflux disease, causing delays in diagnosis and treatment. Although endoscopic findings such as furrows, esophageal mucosa trachealization, and whitish exudates may suggest its presence, this diagnosis should be confirmed histologically based on the presence of more than 15 eosinophils per high-power field and the exclusion of other causes of eosinophilia (parasitic infections, hypereosinophilic syndrome, inflammatory bowel disease, among others) for which treatment could be initiated. Currently, the 3 "D"s ("Drugs, Diet, and Dilation") are considered the fundamental components of treatment. The first 2 components, which involve the use of proton pump inhibitors, corticosteroids, immunosuppressants and empirical diets or guided food elimination based on allergy tests, are more useful in the initial phases, whereas endoscopic dilation is re...
Source: World Journal of Gastroenterology : WJG - Category: Gastroenterology Authors: Tags: World J Gastroenterol Source Type: research

Related Links:

ConclusionThe findings from this study have established the need to improve current education and rehabilitation programmes for patients with CHF by addressing those factors significantly influencing their adherence to diet and medication.
Source: Heart and Lung: The Journal of Acute and Critical Care - Category: Respiratory Medicine Source Type: research
Publication date: Available online 16 November 2019Source: Trends in Endocrinology &MetabolismAuthor(s): Carina Bodden, Anthony J. Hannan, Amy C. ReicheltGlobally, obesity has reached epidemic proportions. The rapidly increasing numbers of overweight people can be traced back to overconsumption of energy-dense, poor-quality foods as well as physical inactivity. This development has far-reaching and costly implications. Not only is obesity associated with serious physiological and psychological complications, but mounting evidence also indicates a ripple effect through generations via epigenetic changes. Parental obesit...
Source: Trends in Endocrinology and Metabolism - Category: Endocrinology Source Type: research
ConclusionsIn contrast to Europe and North America, where R. rosea is the focal species in commerce, the trade in Rhodiola products in China is much more diverse. In the face of growing demand, both effective conservation of wild populations and cultivation are needed.Graphical abstract
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
(Natural News) The ketogenic diet, also known as the keto diet, has surged in popularity in recent years due to its ability to help people lose weight faster. This particular diet involves eating a minimal amount of carbs and high amounts of fat and protein to achieve a metabolic state called ketosis. Ketosis only happens when the body doesn’t have enough...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
Abstract The concentrations of total and proportions of organic mercury were measured in tissues of 355 individuals of 8 species of Southern Ocean squid (Alluroteuthis antarcticus, Bathyteuthis abyssicola, Filippovia knipovitchi, Galiteuthis glacialis, Gonatus antarcticus, Kondakovia longimana, Psychroteuthis glacialis and Slosarczykovia circumantarctica). Squid were caught around South Georgia (Scotia Sea) during 5 cruises, between the austral summers of 2006/07 to 2016/17 to evaluate temporal changes in bioaccumulation and tissue partitioning. Total mercury concentrations varied between 4 ng g-1 and 804 ng...
Source: Chemosphere - Category: Chemistry Authors: Tags: Chemosphere Source Type: research
Nobel S Abstract Perfluorooctanoic acid (PFOA), a global environmental pollutant detected in both wildlife and human populations, has several pathophysiological effects in experimental animals, including hepatotoxicity, immunotoxicity, and developmental toxicity. However, details concerning the tissue distribution of PFOA, in particular at levels relevant to humans, are lacking, which limits our understanding of how humans, and other mammals, may be affected by this compound. Therefore, we characterized the tissue distribution of 14C-PFOA in mice in the same manner as we earlier examined its analogues perfluorooc...
Source: Chemosphere - Category: Chemistry Authors: Tags: Chemosphere Source Type: research
Publication date: Available online 16 November 2019Source: Journal of Functional FoodsAuthor(s): Yue Teng, Yu Wang, Yuan Tian, Yi-ying Chen, Wu-yang Guan, Chun-hong Piao, Yu-hua WangAbstractLactobacillus plantarum LP104 was isolated with excellent antioxidant properties from kimchi. In order to evaluate the role of LP104 in improving hyperlipidemia in high-fat-diet mice, C57BL/6N mice were randomly assigned into three groups treated with different diets: normal chow (Control), HFD, and HFD with L. plantarum LP104. After eight weeks, L. plantarum LP104 treatment significantly reduced HFD-induced body weight gain and the lev...
Source: Journal of Functional Foods - Category: Nutrition Source Type: research
ConclusionsIn conclusion, two of the predictions were partially supported (and hence also partially not supported) and the other three predictions were not supported. We conclude the CIM does not explain the impact of dietary macronutrients on adiposity in mice.
Source: Molecular Metabolism - Category: Endocrinology Source Type: research
Conclusion: Here we discuss the major implications of these findings for the association between microorganisms and cancer, and also between some immune pathologies, like autoimmune diseases, and cancer.
Source: Current Cancer Therapy Reviews - Category: Cancer & Oncology Source Type: research
More News: Acid Reflux | Allergy | Allergy & Immunology | Children | Corticosteroid Therapy | Diets | Environmental Health | Gastroenterology | Gastroesophageal Reflux Disease | Genetics | GERD | Heartburn | Inflammatory Bowel Disease | Nutrition | Parasitic Diseases | Parasitology | Pathology | Pediatrics