Reduced Flow ex vivo Lung Perfusion to Rehabilitate Donation After Cardiac Death Lungs

Current ex vivo lung perfusion (EVLP) protocols aim to achieve perfusion flows of 40% of cardiac output or more. We hypothesized that a lower target flow rate during EVLP would improve graft function and decrease inflammation of donation after circulatory death (DCD) lungs.

Source: The Journal of Heart and Lung Transplantation - September 17, 2019 Category: Transplant Surgery Authors: Jared P. Beller, Matthew R. Byler, Dustin T. Money, William Z. Chancellor, Aimee Zhang, Yunge Zhou, Mark H. Stoler, Adishesh K. Narahari, Alexander Shannon, J Hunter Mehaffey, Curtis G. Tribble, Victor E. Laubach, Irving L. Kron, Mark E. Roeser Tags: Original Pre-Clinical Science Source Type: research