Synthesis of New Cyclazines and 4,5-Diaryl-1H-pyrrol-3(2H)-one unit in Discoipyrroles from Indolizinone-DMAD Cycloadducts

Org. Biomol. Chem., 2019, Accepted Manuscript DOI: 10.1039/C9OB01655D, PaperMuraleedharan Kannoth Manheri, Jais Kurian Reaction of indolizinones with Dimethyl acetylenedicarboxylate gave direct access to 3 ’,8a-dihydrocyclopenta[hi]indolizin-8a-ol and 1H-pyrrol-3(2H)-one in good yields. The former skeleton is a precursor to cyclazine with nitrogen on the periphery, a... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - Category: Molecular Biology Authors: Source Type: research