Cortical reorganization in multiple sclerosis after intrathecal baclofen therapy.

We reported a case of a woman affected by MS and severe spasticity, who performed an fMRI examination, before and after the ITB implantation. The subject showed controlateral motor cortex activation after motor task. After a month of ITB implantation, patient showed ipsilateral and controlateral motor cortex activation although with a broader extension. fMRI examination supported the hypothesis of a central influence in patients who undergo physiotherapy and therapy with ITB.
PMID: 23548099 [PubMed - as supplied by publisher]

Source: Neurocase - April 3, 2013 Category: Neurology Authors: Guerrera S, Morabito R, Baglieri A, Corallo F, Ciurleo R, De Luca R, De Salvo S, Marino MA, Spadaro L, Timpano F, Bramanti P, Marino S Tags: Neurocase Source Type: research