Umbilical cord blood sampling versus admission blood sampling on requirement of blood transfusion in extremely preterm infants

Balasubramanian et  al have addressed an intervention that is feasible and easy doable.1 However, we have a few queries.
Source: The Journal of Pediatrics - Category: Pediatrics Authors: Tags: Letters to the Editor Source Type: research

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Abstract Surgical techniques used to decrease the amount of blood lost during the procedure range from tourniquets to electrocautery and, more recently, the use of antifibrinolytics. Currently, tranexamic acid is the most commonly used antifibrinolytic in arthroplasty procedures. It was previously thought that intravenous tranexamic acid was more effective than topical tranexamic acid, but had an increased risk of thrombosis and cardiac events; however, this study showed that topical tranexamic acid is as effective in decreasing blood loss and the need for a blood transfusion after hybrid fixation total knee arthr...
Source: The Orthopedic Clinics of North America - Category: Orthopaedics Authors: Tags: Orthop Clin North Am Source Type: research
Abstract Cancer is the leading cause of death by disease in developed countries. Children and adolescents with cancer need surgical interventions (ie, biopsy or major surgery) to diagnose, treat, or palliate their malignancies. Surgery is a period of high vulnerability because it stimulates the release of inflammatory mediators, catecholamines, and angiogenesis activators, which coincides with a period of immunosuppression. Thus, during and after surgery, dormant tumors or micrometastasis (ie, minimal residual disease) can grow and become clinically relevant metastasis. Anesthetics (ie, volatile agents, dexmedetom...
Source: Anesthesia and Analgesia - Category: Anesthesiology Authors: Tags: Anesth Analg Source Type: research
AbstractInherited bleeding disorders are not uncommon in pediatric practice: most of them being chronic, require lifelong replacement therapy. To frame a management policy, it is essential to assess the load and pattern of bleeding disorders in the local population. However, there is paucity of data reporting the clinical spectrum of coagulation and platelet function disorders in Indian children. Hence to find out the exact burden and clinico-investigational profile of these patients we conducted this study. In this retrospective case review, detailed clinical information was extracted from case records in 426 children wit...
Source: Indian Journal of Hematology and Blood Transfusion - Category: Hematology Source Type: research
Measles, mumps, and tuberculosis—these are all diseases the general public has long disregarded as active threats. Yet, these highly infectious and potentially life-threatening diseases once considered eradicated have been resurfacing across the United States. Measles, for example, was declared eliminated in 2000 by the CDC, yet this year alone more than 1,200 individual cases have been confirmed in 30 states. This outbreak represents the greatest number of reported cases for the disease in the United States since 1992.1 While the ongoing anti-vaccination movement may not be the cause of these reappearanc...
Source: MDDI - Category: Medical Devices Authors: Tags: Components Source Type: news
The zoonotic hepatitis E virus genotype 3 (HEV-3) may cause human infections in Europe with reservoirs predominately in pigs. In Denmark, HEV-3 is widely spread in pig herds and in pigs at time of slaughter (Breum et al., 2010) (Krog et al., 2019). The transmission of HEV-3 is mainly associated with the consumption of contaminated foodstuff, but transmission by blood transfusion and organ transplantation can also occur (Hewitt et al., 2014). Infection with HEV-3 usually leads to silent seroconversion.
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Source Type: research
Source: Indian Journal of Hematology and Blood Transfusion - Category: Hematology Source Type: research
AbstractOver the past decade, few reports suggested that the drug thalidomide (HbF inducer) may be of value in a subset of transfusion-dependent and non-transfusion dependent thalassemia patients. A cohort of 37 patients with symptomatic β-thalassemia syndrome [14 transfusions dependent thalassemia (TDT), and 23 Non-transfusion dependent Thalassemia (NTDT)], who were unable to pursue conventional therapy with transfusion and chelation, were recruited over 3 years in a center in Iraqi Kurdistan. After taking informed consent, patien ts were put on low dose Thalidomide (2–10 mg/kg), with regular follow up aft...
Source: Indian Journal of Hematology and Blood Transfusion - Category: Hematology Source Type: research
This study aims to analyze the prevalence and to concentrate on the key risk factors that are responsible for hepatitis B virus (HBV), hepatitis C virus (HCV), and human immunodeficiency virus (HIV) infection in patients on HD visiting two dialysis centers in the city of Quetta in southwestern Pakistan. The overall incidence of HBV was found to be 16.1%, the overall incidence of HCV was found to be 43.2%, and two patients (1.6%) were found to be positive for both HBV and HCV. HIV was not found among patients seen at both hospitals during the study period. The main risk factors for development of a viral infection were the ...
Source: Drug Discoveries and Therapeutics - Category: Drugs & Pharmacology Tags: Drug Discov Ther Source Type: research
AbstractAbdomino-perineal resection (APR) for rectal cancer is challenging, due to the difficult exposure of the surgical field. Many investigations proved worst results in terms of circumferential resection margin (CRM) involvement compared to rectal anterior resection (RAR) with total mesorectal excision (TME). Extralevator abdomino-perineal excision (ELAPE) improved oncologic outcomes, but is burdened by important limitations (positioning, wound closure). Applying the concept of transanal minimally invasive surgery (TAMIS) and the experience in transanal TME (TaTME) to the perineal phase of APR could overcome these limi...
Source: Updates in Surgery - Category: Surgery Source Type: research
The objective of this study was to evaluate the anti-ZIKV IgG prevalence in blood donors from the Northeast region of the S ão Paulo State, Brazil, which experienced a ZIKV outbreak in 2016.
Source: Journal of Infection - Category: Infectious Diseases Authors: Tags: RESEARCH ARTICLE Source Type: research
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