Does Botox reduce the frequency of chronic migraine?

Doesn’t it seem like Botox is showing up everywhere as a medical treatment? Botox is a brand of botulinum neurotoxin (BoNT), a protein substance originally derived from the bacterium Clostridium botulinum. In its original form it was the toxin responsible for botulism, the paralyzing illness often caused by eating contaminated food. BoNT is now used to treat a number of medical conditions including muscle spasms, excessive sweating, overactive bladder, and some eye muscle conditions. However, one of its most common uses is in the preventive treatment of chronic migraine. Chronic migraine, defined as headache occurring more than 15 days a month for more than three months, is rare, affecting only about 3% of the migraine population. Nonetheless, since migraine itself is so common, this condition ends up affecting a large number of people and can be extremely debilitating. A recent meta-analysis pooled the results of multiple prior studies to investigate the usefulness of Botox, a brand of BoNT, in reducing the frequency of chronic migraine. The results suggested that there was benefit from this treatment; it not only improved quality of life and significantly reduced the frequency of chronic migraine headaches, but did so with few and mild side effects. How might BoNT work to prevent chronic migraine? Botox was introduced for treatment of chronic migraine in 2000, after some people receiving injections for cosmetic treatment of facial lines reported improvement of headach...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Drugs and Supplements Headache Source Type: blogs

Related Links:

CONCLUSIONS This study contributed to the knowledge on the profile of confirmed cases of high severity yellow fever. The main factors associated with death were changes in renal excretion and elevated serum transaminases, especially ALT. High lethality emphasizes the need for early diagnosis and treatment, and the importance of increasing vaccination coverage.RESUMO OBJETIVO Descrever o perfil cl ínico-epidemiológico dos casos confirmados de febre amarela internados em hospital geral de referência para doenças infecciosas no estado do Rio de Janeiro, Brasil, de 11 de março de 2017 a 15 de ...
Source: Revista de Saude Publica - Category: International Medicine & Public Health Source Type: research
Locations - National Spine &Pain Centers treatingpain.com Hey all, anyone familiar with the National Spine and Pain practices operating out of the maryland and northern virginia area? A good practice to work for? Any idea what the compensation is for the pain docs working there?
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Pain Medicine Source Type: forums
Source: Clinical Drug Investigation - Category: Drugs & Pharmacology Source Type: research
AbstractLactotroph adenomas, also called prolactinomas and prolactin-secreting adenomas, constitute nearly 80% of functioning pituitary tumors and about 30 –50% of all adenomas in the clinical practice. Lactotroph adenomas occur in the general population at a prevalence of 45/100,000, are more common in women, but also involve men and children of both sexes. Most lactotroph adenomas are microadenomas occurring in reproductive-age women who present wi th oligo/amenorrhea, galactorrhea, and infertility. In men and elderly women, lactotroph adenomas are usually macroadenomas and are most commonly associated with symptom...
Source: Pituitary - Category: Endocrinology Source Type: research
AbstractFremanezumab (fremanezumab-vfrm; Ajovy®), a monoclonal antibody that targets calcitonin gene-related peptide (CGRP), is indicated for the prevention of migraine in adults in the EU and USA. Subcutaneous fremanezumab 225  mg once monthly or 675 mg once every 3 months was effective in reducing monthly migraine days or headache days in patients with episodic or chronic migraine in pivotal, 12-week clinical trials. Both regimens also reduce acute headache medication use and headache-related disability. Improvements were maintained through ≤ 52 weeks of additional treatment in a longer-...
Source: Drugs and Therapy Perspectives - Category: Drugs & Pharmacology Source Type: research
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
Arizona will receive $2.8 million of a nearly $117 million settlement that Johnson&Johnson has reached over safety concerns and misleading marketing of a surgical mesh used to treat urinary incontinence and other pelvic floor disorders, Arizona Attorney General Mark Brnovich said. The nationwide settlement involved transvaginal surgical meshes implanted to treat a variety of pelvic floor issues. But state prosecutors in 41 states and the District of Columbia said it caused pain, incontinence,…
Source: bizjournals.com Health Care:Biotechnology headlines - Category: Biotechnology Authors: Source Type: news
Conclusions: Results suggest TCC may have a small positive effect on early outcomes, but use of the services was highly variable among sites. Level of Evidence: Therapeutic Level I. See Instructions for Authors for a complete description of levels of evidence.
Source: Journal of Orthopaedic Trauma - Category: Orthopaedics Tags: Original Article Source Type: research
STOMACH bloating is usually remedied by making simple dietary changes. If quick fixes do not alleviate the tummy swelling, this may signal a more serious condition, including one that specifically affects women.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Publication date: Available online 20 October 2019Source: The LancetAuthor(s): Daniel I Sessler, Lijian Pei, Yuguang Huang, Edith Fleischmann, Peter Marhofer, Andrea Kurz, Douglas B Mayers, Tanja A Meyer-Treschan, Martin Grady, Ern Yu Tan, Sabry Ayad, Edward J Mascha, Donal J Buggy, Gang Tan, Zhiyong Zhang, Helen Keane, Maurice Stokes, Oliver Zotti, Michael Gnant, Silvia Perez-ProttoSummaryBackgroundThree perioperative factors impair host defence against recurrence during cancer surgery: the surgical stress response, use of volatile anaesthetic, and opioids for analgesia. All factors are ameliorated by regional anaesthesia...
Source: The Lancet - Category: General Medicine Source Type: research
More News: Blogging | Botox | Botulism | Brain | Chemistry | Chronic Pain | Genetics | Harvard | Headache | Health | Health Insurance | Insurance | Migraine | Neurology | Overactive Bladder | Overactive Bladder Syndrome | Pain | Pain Management | Poisoning | Study