Population prevalence of individuals meeting criteria for hereditary breast and ovarian cancer testing
ConclusionsThis study quantifies the population ‐based prevalence of HBOC criteria using objectively determined genealogy and cancer incidence data. Sporadic breast cancer likely represents a portion of the high prevalence of family cancer history seen in this study. These results underline the importance of establishing presence of a deleterio us mutation in an affected family member, per NCCN guidelines, before testing unaffected relatives.
Source: Cancer Medicine - Category: Cancer & Oncology Authors: Samantha Greenberg,
Saundra S. Buys,
Sandra L. Edwards,
Whitney Espinel,
Alison Fraser,
Amanda Gammon,
Brent Hafen,
Kimberly A. Herget,
Wendy Kohlmann,
Camille Roundy,
Carol Sweeney Tags: ORIGINAL RESEARCH Source Type: research
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