GSE129162 Non-CYP2D6 variants selected by GWAS improved the prediction of impaired tamoxifen metabolism in breast cancer patients

Conclusions: The four novel SNPs, tested alone or in addition to CYP2D6 genotype, improved the prediction of impaired tamoxifen to endoxifen metabolism, allowing for adjustments in dosing regimen before the treatment begins.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Genome variation profiling by SNP array Homo sapiens Source Type: research