Association of Cytomegalovirus and Toxoplasma Antibody Titers With Bipolar Disorder

This case-control study analyzes the association of long-term antibody response to cytomegalovirus, Toxoplasma gondii, and measles and of C-reactive protein level with bipolar disorder.
Source: JAMA Psychiatry - Category: Psychiatry Source Type: research

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In this study, we investigated the interrelations among interleukin (IL)-6 cytokine level, grey matter (GM) volume of the anterior cingulated cortex (ACC), and attention function among offspring of parents diagnosed with BD. The offspring were categorized as being either asymptomatic or symptomatic based on whether they manifested pre-defined sub-threshold mood symptoms. We found that the symptomatic offspring showed significantly higher serum levels of IL-6 than the asymptomatic offspring (F (1, 59) = 67.65, p0.05). Mediation analyses revealed that the GM volume of the rostral ACC significantly mediated the negative assoc...
Source: Brain, Behavior, and Immunity - Category: Neurology Source Type: research
ConclusionsThe current rapid, multi-slice acquisition and real-time implementation of temperature and displacement visualization may be useful in clinical practices. It may help defining operational safety margins, improving therapy precision and efficacy. Simulations were in good agreement with experimental data and may thus be used prior treatment for procedure planning.
Source: NeuroImage - Category: Neuroscience Source Type: research
We examined the concentrations of chemokines and related substances in the brain tissue from these two groups using the Bio-Plex Pro™ Human Chemokine Panel 40-Plex. We performed multiple regression analysis with covariates. The levels of CCL1, CCL8, CCL13, CCL15, CCL17, CCL19, CCL20, CXCL11, and IL-10 were significantly decreased, whereas the IL-16 levels were significantly increased in the suicide completers after adjustment with the Benjamini-Hochberg method to control for type Ⅰ errors (Q 
Source: Journal of Psychiatric Research - Category: Psychiatry Source Type: research
It's been a good year for the measles virus with more reported cases in the U.S. than in any other year since 1992.
Source: Forbes.com Healthcare News - Category: Pharmaceuticals Authors: Source Type: news
CONCLUSION: Despite good interrater variability and convenient usage of the suggested X‑ray assessment system, this approach did not enable the identification of any associations by which a TM and, therefore, a possible straightforward or complicated treatment pathway could be predicted. Attention should possibly be paid to a rotation of the cuff during implantation with a lateral position of the stimulation lead. PMID: 31598770 [PubMed - as supplied by publisher]
Source: HNO - Category: ENT & OMF Tags: HNO Source Type: research
Publication date: 2019Source: International Review of Neurobiology, Volume 147Author(s): Kangguang Lin, Tao LiuAbstractPeople with Bipolar disorder (BD) often have a sedentary lifestyle and low level of physical activity which in part contribute to the high co-occurrence of medical diseases including cardiovascular disease, type 2 diabetes, and metabolic syndrome, etc. Exercise especially aerobic exercise may be beneficial not only to mental health but also physical health outcomes. Targeting barriers for exercise such as high BMI and making the best use of facilitators (e.g., concept of fitness) can result in higher level...
Source: International Review of Neurobiology - Category: Neuroscience Source Type: research
This study determines the relationship between cognition and vascular burden in patients with SMD. Methods: Sixty SMD patients (61% men, mean age: 46) attending a psychosocial rehabilitation centre were included. We evaluated sociodemographic, clinical, laboratory, quality of life and functionality characteristics. And we analysed the association between cognitive performance and vascular burden. Results: SMD diagnoses were: 41.7% schizophrenia, 20.0% bipolar, 5.0% schizoaffective, 21.7% depressive and 11.7% other. Cognitive impairment was present in 55% of the cases. The average vascular burden was 3.2. Patients with cogn...
Source: Cognitive Neuropsychiatry - Category: Psychiatry Tags: Cogn Neuropsychiatry Source Type: research
Publication date: November 2019Source: The Lancet Global Health, Volume 7, Issue 11Author(s): Andrew Clark, Jacqueline Tate, Umesh Parashar, Mark Jit, Mateusz Hasso-Agopsowicz, Nicholas Henschke, Benjamin Lopman, Kevin Van Zandvoort, Clint Pecenka, Paul Fine, Colin SandersonSummaryBackgroundInfant rotavirus vaccines have led to substantial reductions in hospital admissions and deaths due to gastroenteritis, but some studies have reported an elevated risk of intussusception, a rare bowel disorder. This analysis aimed to provide evidence on the potential mortality reduction benefits and intussusception risks of current rotav...
Source: The Lancet Global Health - Category: International Medicine & Public Health Source Type: research
Latest WHO global data show that reported cases of measles — which is one of the world's most contagious diseases — rose by 300 per cent globally in the first three months of this year compared to the same period in 2018.
Source: CBC | Health - Category: Consumer Health News Tags: News/Health Source Type: news
The United States is currently facing the largest measles outbreak in three decades, with more than 1,200 cases reported to the Centers for Disease Control. The spread of that disease is a mere symptom of one of the most dangerous pandemics of our time: misinformation. Social media transformed the information age, kicking it into overdrive. […]Find jobs at  Careers by KevinMD.com.  Search thousands of physician, PA, NP, and CRNA jobs now.  Learn more.
Source: Kevin, M.D. - Medical Weblog - Category: General Medicine Authors: Tags: Physician Primary Care Public Health & Policy Source Type: blogs
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