A high frequency of Gallid herpesvirus-2 co-infection with Reticuloendotheliosis virusis associated with high tumor rates in Chinese chicken farms

Publication date: October 2019Source: Veterinary Microbiology, Volume 237Author(s): Yanping Zhang, Zhenghao Yu, Xingge Lan, Feng Zhang, Qi Wang, Kai Li, Qing Pan, Yulong Gao, Xiaole Qi, Hong-yu Cui, Yongqiang Wang, Li Gao, Xiaomei Wang, Changjun LiuAbstractThe prevalence of Marek’s disease (MD) caused by Gallid herpesvirus-2 (GaHV-2) has been increasing in chickens in China despite universal vaccination. Among the possible reasons for this trend, of Reticuloendotheliosis virus (REV) contamination in vaccines could lead to co-infection and reduce the vaccine efficacy. Here, we report the epidemiological findings of our continuous surveillance of MD, and an examination of the effects of REV and/or GaHV-2 co-infection. A total of 1230 samples were collected between 2011 and 2015 from 305 flocks covering many of the chicken-raising regions of China. Among these, 606 samples were determined to be GaHV-2-positive, 13.0% of which were found to be co-infected with REV from 18.8% of the flocks. One GaHV-2 strain (HS/1412), a REV strain (HS/1412R), and a GaHV-2 and REV-co-infected strain (HS/1412 GR) were isolated from different chickens of a GaHV-2 and REV co-infected flock. Pathogenicity tests showed that HS/1412 and HS/1412 GR caused disease in all chickens and that HS/1412R induced morbidity in 84.6% of the infected chickens. HS/1412 GR induced 100% mortality and 76.9% tumor formation, which were significantly higher frequencies than those observed with strain HS/1412 (...
Source: Veterinary Microbiology - Category: Veterinary Research Source Type: research

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Abstract Peste des petits ruminants (PPR) is an acute transboundary infectious viral disease affecting domestic and wild small ruminants' species besides camels reared in Africa, Asia and the Middle East. The virus is a serious paramount challenge to the sustainable agriculture advancement in the developing world. The disease outbreak was also detected for the first time in the European Union namely in Bulgaria at 2018. Therefore, the disease has lately been aimed for eradication with the purpose of worldwide clearance by 2030. Radically, the vaccines needed for effectively accomplishing this aim are presently con...
Source: Virus Research - Category: Virology Authors: Tags: Virus Res Source Type: research
Publication date: Available online 19 September 2019Source: Preventive Veterinary MedicineAuthor(s): Margaret LaFerla Jenni, Peter Woodward, Hayley Yaglom, Craig Levy, Sally Ann Iverson, Melissa Kretschmer, Nicole Jarrett, Elizabeth Dooley, Jigna Narang, Heather VenkatAbstractLeptospirosis, caused by Leptospira spp., is a zoonotic bacterial disease important to both human and animal health. Six pathogenic serovars are currently known to commonly infect and cause disease in dogs in the United States. While canine leptospirosis infection is historically rare in Arizona (≤5 cases reported annually) (ADHS unpublished data) ...
Source: Preventive Veterinary Medicine - Category: Veterinary Research Source Type: research
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Source: Preventive Veterinary Medicine - Category: Veterinary Research Source Type: research
Publication date: Available online 5 September 2019Source: Veterinary MicrobiologyAuthor(s): Yanping Zhang, Zhenghao Yu, Xingge Lan, Feng Zhang, Qi Wang, Kai Li, Qing Pan, Yulong Gao, Xiaole Qi, Hong-yu Cui, Yongqiang Wang, Li Gao, Xiaomei Wang, Changjun LiuAbstractThe prevalence of Marek’s disease (MD) caused by Gallid herpesvirus-2 (GaHV-2) has been increasing in chickens in China despite universal vaccination. Among the possible reasons for this trend, of Reticuloendotheliosis virus (REV) contamination in vaccines could lead to co-infection and reduce the vaccine efficacy. Here, we report the epidemiological findi...
Source: Veterinary Microbiology - Category: Veterinary Research Source Type: research
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Source: Viruses - Category: Virology Authors: Tags: Review Source Type: research
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Source: Preventive Veterinary Medicine - Category: Veterinary Research Source Type: research
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Source: Vaccine - Category: Allergy & Immunology Authors: Tags: Vaccine Source Type: research
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Source: NIH OTT Licensing Opportunities - Category: Research Authors: Source Type: research
AbstractBetween July and August 2018, two outbreaks of infectious laryngotracheitis caused the death of over 116,000 commercial poultry (layers and broilers) near the city of Windhoek, Namibia. A third outbreak occurred in September 2018 in the north of the country approximately 800  km from the original outbreaks. Sample collection and molecular epidemiological analyses revealed that the outbreaks were most likely caused by poor vaccination practices leading to the reversion to virulence of an ILT vaccine strain. The analyses also indicate that inaccurate declarations were ma de by one of the farms involved and that ...
Source: Tropical Animal Health and Production - Category: Veterinary Research Source Type: research
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Source: Preventive Veterinary Medicine - Category: Veterinary Research Source Type: research
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