Usefulness of the frontal lobe bottom and cerebellum tuber vermis line as an alternative clue to set the axial angle parallel to the AC –PC line in I-123 IMP SPECT imaging: a retrospective study

AbstractWe aimed to investigate whether the frontal lobe bottom and cerebellum tuber vermis (FLB –CTV) line on brain perfusion scintigraphy, using iodine-123 isopropyl iodoamphetamine single photon emission computed tomography (I-123 IMP SPECT) images, is useful to determine an axial angle parallel to the anterior commissure-posterior commissure (AC–PC) line. We measured the angular differe nces between the AC–PC line and the FLB–CTV line on midsagittal brain magnetic resonance imaging (MRI) scans of 100 patients. We also evaluated the angular differences of the FLB–CTV line between the IMP SPECT images and the computed tomography for attenuation correction (CTAC) images in the s ame 100 patients, using a reference line on the CTAC images. Furthermore, the inter-reader reproducibility of the FLB–CTV line measurements on IMP SPECT images of 50 patients between two readers was evaluated using the intra-class correlation coefficient (ICC) and 95% confidence interval (CI). The mean and standard deviation of the angular differences between the AC–PC and FLB–CTV lines on midsagittal brain MRI scans were − 1.24° and 1.14°, respectively. The mean and the standard deviation of the angular differences of the FLB–CTV line in the IMP SPECT and CTAC images were 0.87° a nd 0.48°, respectively. The ICC of the FLB–CTV line measurements on IMP SPECT images was 0.99 (95% CI 0.98–0.99). We demonstrated that the FLB–CTV line was almost parallel to the AC–PC line a...
Source: Radiological Physics and Technology - Category: Physics Source Type: research