Phenotypic and molecular characteristics of carbapenem-non-susceptible Enterobacteriaceae from a teaching hospital in Wenzhou, southern China.

This study suggests that KPC-2-type carbapenemase is the main contributor to carbapenems resistance in carbapenemase-producing Enterobacteriaceae, and that ESBL, AmpC β-lactamase overproduction, and porin loss contribute to the resistance level among these isolates; in carbapenemase-non-producing Enterobacteriaceae, ESBL, AmpC enzyme, and porin loss contribute to the carbapenems resistance of Enterobacteriaceae, especially the ertapenem resistance of Enterobacter cloacae. PMID: 23514904 [PubMed - in process]

http://www.ncbi.nlm.nih.gov/pubmed/23514904?dopt=Abstract

Source: Japanese Journal of Infectious Diseases - May 25, 2013 Category: Infectious Diseases Authors: Zhou T, Zhang X, Guo M, Ye J, Lu Y, Bao Q, Chi W Tags: Jpn J Infect Dis Source Type: research