Detection of Chlamydia trachomatis by Immunological and Genetic Methods in Female Sex Workers and the Local Female Population of Reproductive Age in Mymensingh, Bangladesh.

Detection of Chlamydia trachomatis by Immunological and Genetic Methods in Female Sex Workers and the Local Female Population of Reproductive Age in Mymensingh, Bangladesh. Jpn J Infect Dis. 2013;66(3):256-9 Authors: Hoque SM, Hossain MA, Paul SK, Mahmud MC, Ahmed S, Mahmud NU, Khan ER, Sakib MA, Ghosh S, Kobayashi N Abstract To investigate the accurate prevalence of genital Chlamydia trachomatis infection in Mymensingh, a local area in central-northern Bangladesh, 40 female sex workers (FSW) and 110 sexually active women (SAW, non-FSW) of reproductive age from a local community with clinical symptoms were examined by an immunochromatography test (ICT) and plasmid-based polymerase chain reaction (PCR) during a 1-year period from July 2011 to June 2012 using the endocervical swab as a specimen. By ICT and/or PCR, the C. trachomatis detection rate was 58% and 27% in FSW and SAW, respectively, showing a significant difference (P < 0.01). Two C. trachomatis strains from FSW were determined to be serovar D by ompA-based PCR and sequencing analysis. The highest prevalence was found among women aged 15 to 35 years. A lower socioeconomic status was considered to be an important risk factor for C. trachomatis infection in FSW but not in SAW. This is the first study to determine the prevalence of C. trachomatis infections in FSW and SAW in the same local area in Bangladesh. PMID: 23698492 [PubMed - in process]
Source: Japanese Journal of Infectious Diseases - Category: Infectious Diseases Authors: Tags: Jpn J Infect Dis Source Type: research