Voxel-based statistical analysis and quantification of amyloid PET in the Japanese Alzheimer ’s disease neuroimaging initiative (J-ADNI) multi-center study

ConclusionsWe examined the usefulness of voxel-based statistical analysis for amyloid PET. This method provides objectiveZ-score maps andZ-sum values, which were observed to be helpful as an adjunct to visual interpretation especially for cases with mild or limited A β accumulation. This approach could improve the Aβ detection sensitivity, reduce inter-reader variability, and allow for detailed monitoring of Aβ deposition.Trial registrationThe number of the J-ADNI study isUMIN000001374
Source: EJNMMI Research - Category: Radiology Source Type: research