New Kid on the Block- Mini Beam Radiation Treatment- Final Report of a Randomized Phase III Study of Treating Canine Denovo Brain Tumors

The challenge in treating malignant brain neoplasms lies in eradicating tumor while minimizing treatment-related damage to normal adjacent brain. These tumors are currently treated with conventional radiation therapy techniques, which control the tumor but are associated with considerable side effects. Synchrotron generated micro-beam radiation therapy (SMBRT) has shown promising results in preserving brain architecture while killing tumor cells, however physical characteristics of SMBRT limit its use.
Source: International Journal of Radiation Oncology * Biology * Physics - Category: Radiology Authors: Source Type: research

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Glioblastoma is the most common and aggressive brain tumour in adults with a median overall survival of only 14  months after standard therapy with radiation therapy (IR) and temozolomide (TMZ). In a novel mult...
Source: Journal of Experimental and Clinical Cancer Research - Category: Cancer & Oncology Authors: Tags: Research Source Type: research
A radiation therapy (RT) treatment that combines radiation with chemotherapy...Read more on AuntMinnie.comRelated Reading: Intelerad to launch enterprise software at RANZCR 2019 RANZCR issues final version of ethical AI guidelines RANZCR praises government pledge to support MRI access RANZCR proposes ethical guidelines for AI Virtual reality may help plan, guide glioma resection
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
A radiation therapy (RT) treatment that combines radiation with chemotherapy...Read more on AuntMinnie.comRelated Reading: Intelerad to launch enterprise software at RANZCR 2019 RANZCR issues final version of ethical AI guidelines RANZCR praises government pledge to support MRI access RANZCR proposes ethical guidelines for AI Virtual reality may help plan, guide glioma resection
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
Conditions:   Primary Brain Tumor;   Radiation Toxicity Intervention:   Radiation: Cognitive testing Sponsor:   University of Aarhus Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
We investigated by immunohistochemistry the clinical significance and the evolution of Oligodendrocyte lineage transcription factor 2 (OLIG2) and cyclin D2 (CCND2) protein expression, two markers highly specific of glioma stem cells, on a cohort of human paired glioblastoma samples comparing initial resections with recurrent tumors after radiation therapy alone or radio ‐chemotherapy with temozolomide according to the Stupp regimen. Our study highlighted for the first time the prognostic value of high nuclear expression of CCND2 at initial surgery which is associated with early mortality and patients for whom nuclear exp...
Source: Cancer Medicine - Category: Cancer & Oncology Authors: Tags: ORIGINAL RESEARCH Source Type: research
ConclusionsCoverage guidelines for IMRT, SRS, SABR, and PBT vary across 5 major insurance providers and may be substantially discordant compared with ASTRO coverage guidelines. There remain several specific areas where ongoing and future dialogues between ASTRO members, payers, and policymakers remain essential.
Source: Practical Radiation Oncology - Category: Cancer & Oncology Source Type: research
This study recruited two centers with expertise in treating pediatric brain tumors with robotic radiation delivery system photon therapy and proton therapy, respectively, to study the plan quality and the dose deposition characteristics of robotic radiation delivery system photon and intensity modulated proton therapy (IMPT) plans.Methods and MaterialsA total of 18 patients clinically treated with robotic radiation delivery system were planned with intensity-modulated-proton-therapy (IMPT). Cases were planned per the standard of care of each institution but, respected the same planning objectives. The comparison was perfor...
Source: Practical Radiation Oncology - Category: Cancer & Oncology Source Type: research
ROCHESTER, Minn. -- Mayo Clinic physicians will present findings at the American Society for Therapeutic Radiology and Oncology annual meeting Sept. 15-18 in Chicago. Key Mayo Clinic-led studies include: Prolonged radiation therapy does not improve brain tumor control Embargoed until Sunday, Sept. 15, at 1 p.m. CDT Prolonged radiation therapy for brain cancer patients does [...]
Source: News from Mayo Clinic - Category: Databases & Libraries Source Type: news
We present an open-source WMPL tool, implemented in the package Diffusion Imaging in Python (DIPY), and code to convert the resulting WMPL map to anisotropic contours for RT in a commercial treatment planning system.
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
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