Malaria in Pregnancy: What the Obstetric Provider in Nonendemic Areas Needs to Know
Conclusions and Relevance Malaria in pregnancy causes significant perinatal complications. Obstetric providers should be aware of the impact and how to prevent and treat malaria infection during pregnancy. Malaria infection should be suspected in women with concerning symptoms and recent travel to endemic areas. Providers should know the management of uncomplicated and severe malarial infection in pregnancy. Target Audience Obstetricians and gynecologists, family physicians. Learning Objectives After completing this activity, the learner should be better able to assess the adverse pregnancy outcomes associated with malarial infection; evaluate and manage patients traveling to endemic areas during pregnancy; and formulate a treatment plan for acute malaria infection.
Publication date: Available online 22 January 2020Source: Revista Española de Cardiología (English Edition)Author(s): Ernesto Valero, Jessika González-D’Gregorio, Nieves Carbonell, Mónica García-Simón, José Ferreres, Juan Sanchis
Conclusions: Clinical, laboratory and radiological features of histoplasmosis can mimic other conditions, resulting in unnecessary invasive diagnostic procedures. However, a history of travel to endemic areas and of exposure to risk factors (such as visits to caves and presence of bats) should trigger the clinical suspicion of histoplasmosis. Treatment may be indicated in severe or prolonged disease. PMID: 31959091 [PubMed - as supplied by publisher]
CONCLUSIONS: Arabic-speaking women from Arab countries have higher risks of stillbirth compared with the French and English majority in Quebec. Strategies to reduce stillbirth risk among Arabic speakers should focus on improving identification of causes of death. PMID: 31968204 [PubMed - as supplied by publisher]
Pregnant women need to receive vaccines during pregnancy to keep themselves and their infants safe. Barriers to receiving vaccines, such as lack of insurance coverage, need to be removed so mothers and infants can be protected.
This report describes that birth defects potentially related to Zika virus infection during pregnancy increased fourfold in Puerto Rico and the U.S. Virgin Islands, areas with widespread local transmission of Zika virus during the study period.
ConclusionsMarried girls expressed more positive outcomes in their marriage than they did for negative outcomes despite their general perception of their marriage being early. Implications for interventions and policy decision making are discussed.
In this study, we investigate the dynamics of OBs in activated gametocytes of Plasmodium falciparum and Plasmodium yoelii using the female OB-specific marker protein, G377. After activation, female gametocyte OBs migrate to the parasite surface and fuse to form large vesicles beneath the parasite plasma membrane. At the marginal region of female gametocytes, fused vesicles secrete contents by exocytosis into the parasitophorous vacuole space, prior to parasite egress via the break-down of the erythrocyte membrane. This is the first detailed description of how proteins are transported through osmiophilic bodies.
Publication date: Available online 22 January 2020Source: International Journal for Parasitology: Parasites and WildlifeAuthor(s): Ronel Pienaar, P. Christo Troskie, Antoinette I. Josemans, Fred T. Potgieter, Boitumelo B. Maboko, Abdalla A. Latif, Ben J. MansAbstractThe Theileria are apicomplexan parasites transmitted by ticks to vertebrate hosts. Most Theileria species exhibit some form of host or vector specificity, since under endemic conditions only a limited number of tick species act as vectors and not all vertebrate hosts are able to maintain a persistent carrier state. Data for Theileria sp. (buffalo) suggest host ...
(Abstracted from Lancet 2019;393:1428–1439.) In Africa, malaria in pregnancy presents a risk to 50 million women each year due to Plasmodium falciparum infection. Although women in endemic areas are typically asymptomatic when infected with malaria parasites, the infection is associated with maternal anemia and adverse birth outcomes including miscarriage, stillbirth, preterm birth, low birth weight, and infant mortality.
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog aka Tropical Travel Trouble 007 When you think tropical medicine, malaria has to be near the top. It can be fairly complex and fortunately treatment has become a lot simpler. This post is designed to walk you through the basic principals with links to more in depth teaching if your niche is travel medicine, laboratory diagnostics or management of severe or cerebral malaria. If you stubbled on this post while drinking a cup of tea or sitting on the throne and want a fe...