Monthly Sulfadoxine–Pyrimethamine Versus Dihydroartemisinin-Piperaquine for Intermittent Preventive Treatment of Malaria in Pregnancy: A Double-blind, Randomised, Controlled, Superiority Trial

(Abstracted from Lancet 2019;393:1428–1439.) In Africa, malaria in pregnancy presents a risk to 50 million women each year due to Plasmodium falciparum infection. Although women in endemic areas are typically asymptomatic when infected with malaria parasites, the infection is associated with maternal anemia and adverse birth outcomes including miscarriage, stillbirth, preterm birth, low birth weight, and infant mortality.
Source: Obstetrical and Gynecological Survey - Category: OBGYN Tags: OBSTETRICS: MEDICAL COMPLICATIONS OF PREGNANCY Source Type: research

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ConclusionsTB can have varied presentation and therefore it is essential to keep tubercular infection in differential diagnosis while working up for any infective pathology. Conservative treatment produces good results in vast majority of cases. Surgery is reserved for select indications.
Source: Journal of Clinical Orthopaedics and Trauma - Category: Orthopaedics Source Type: research
Publication date: Available online 22 January 2020Source: Pregnancy HypertensionAuthor(s): Fitriana Murriya Ekawati, Ova Emilia, Shaun Brennecke, Jane Gunn, Sharon Licqurish, Phyllis LauAbstractGlobally, almost maternal mortality caused by HDP occurs in low to middle-income countries (LMIC); yet, limited guidance is available to local primary care practitioners who are usually the main health care providers. This review examined existing international practice guidelines to identify potential practices to improve HDP management in Indonesian primary care. We performed a structured literature search strategies and snowballi...
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - Category: OBGYN Source Type: research
Publication date: Available online 22 January 2020Source: European Journal of Obstetrics &Gynecology and Reproductive BiologyAuthor(s): Amihai Rottenstreich, Misgav Rottenstreich, Zvi Ehrlich, Yosef Ezra, David Mankuta, Simcha Yagel, Doron Kabiri, Uriel Elchalal, Gabriel LevinAbstractObjectiveHistory of prior preterm birth (PTB) represents one of the strongest risk factors for recurrent PTB. Nevertheless, whether the occurrence of PTB in multifetal gestation is associated with increased risk of PTB in subsequent pregnancies remains unclear. We aimed to determine the recurrence risk of PTB in a subsequent singleton preg...
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - Category: OBGYN Source Type: research
ConclusionMaternal colonization of ESBL-producing bacteria is an important risk factor for transmission. The vaginal presence of ESBL-producing bacteria during pregnancy is associated with preterm birth and pPROM, which shows the need for clear diagnostic and therapeutic guidelines.
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - Category: OBGYN Source Type: research
This study closed early due to accrual and is registered with the UMIN Clinical Trials Registry (UMIN000011099).FindingsBetween Sept 20, 2013 and July 12, 2016, 68 patients who had a deep molecular response after receiving first-line dasatinib for at least 24 months were enrolled and assigned to the consolidation phase. Nine patients were excluded during the consolidation phase and one patient was excluded after study completion because of meeting exclusion criteria. 58 patients discontinued dasatinib and were assessed. 32 (55%) of 58 patients had treatment-free remission at 6 months after dasatinib discontinuation, and me...
Source: The Lancet Haematology - Category: Hematology Source Type: research
Conditions:   Hypertension in Pregnancy;   Preeclampsia Severe;   Gestational Hypertension;   Postpartum Preeclampsia;   Postpartum Interventions:   Drug: NIFEdipine ER;   Drug: Enalapril Sponsor:   Brigham and Women's Hospital Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Publication date: Available online 21 January 2020Source: Journal of Herbal MedicineAuthor(s): Ana Margarida Rodrigues, Pedro Luis Vieira Falé, Paulo Madeira, Rita Pacheco, Maria Helena Florêncio, Lia Ascensão, Maria Luisa Marques SerralheiroAbstractSantolina impressa Hoffmanns &Link is an aromatic Asteraceae species endemic to the southwest of Portugal. It is used in folk medicine as an herbal tea for gastrointestinal ailments and mouthwash antiseptic. The present study aimed to relate the chemical composition of decoctions from the aerial parts S. impressa with their antiacetylcholinesterase, anti...
Source: Journal of Herbal Medicine - Category: Complementary Medicine Source Type: research
Publication date: Available online 21 January 2020Source: Journal of Applied Research on Medicinal and Aromatic PlantsAuthor(s): Efstathia Patelou, Paschalina Chatzopoulou, Alexios N. Polidoros, Photini V. MylonaAbstractSideritis raeseri Boiss. &Heldr is a subalpine/alpine plant species endemic to the southern part of the Balkan Peninsula. Mountain tea (S. raeseri) is a traditional medical remedy as a decoction of high value and a source of essential oils beneficial to human health. Recent findings of Sideritis active constituents in preventive therapy of osteoporosis, cancer and neurodegenerative diseases have increas...
Source: Journal of Applied Research on Medicinal and Aromatic Plants - Category: Complementary Medicine Source Type: research
ConclusionWe did not observe an increased risk of pregnancy losses or malformations among women with asthma. However, we found an association between asthma severity and SGA; and between exacerbations late in pregnancy and preterm delivery and NICU admission.
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
People who have been pregnant or have breastfed a baby are less likely to enter the menopause before the age of 45, a study of 108,000 people suggests
Source: New Scientist - Health - Category: Consumer Health News Source Type: research
More News: African Health | Anemia | Endemics | Malaria | Miscarriage | OBGYN | Parasitic Diseases | Parasitology | Pregnancy | Women