Renal denervation as an adjunctive therapy to cardiac sympathetic denervation for ablation refractory ventricular tachycardia

Autonomic modulation is finding an increasing role in the treatment of ventricular arrhythmias. Renal denervation (RDN) has been described as a treatment modality for refractory ventricular tachycardia (VT) in case series.
Source: Heart Rhythm - Category: Cardiology Authors: Source Type: research

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Conclusion: Video-assisted CSD should be considered as a treatment option for patients with potentially dangerous arrhythmias that do not respond to conventional treatment, especially in recurrent ventricular tachycardia. PMID: 31588139 [PubMed - in process]
Source: Archivos de Cardiologia de Mexico - Category: Cardiology Authors: Tags: Arch Cardiol Mex Source Type: research
The demonstrated effectiveness of implantable cardioverter-defibrillators (ICDs) for primary and secondary preventions of sudden cardiac death has resulted in an increasing number of patients presenting with recurrent, appropriate ICD shocks for ventricular tachycardia VT.(1) In a selected group of VT patients such as those included in the study by Bradfield and colleagues (2) in this issue of Heart Rhythm, autonomic modulation is considered as adjunctive treatment option after failed catheter-based VT ablation and anti-arrhythmic drug therapy.
Source: Heart Rhythm - Category: Cardiology Authors: Source Type: research
Autonomic modulation is finding an increasing role in the treatment of ventricular arrhythmias. Renal denervation (RDN) has been described as a treatment modality for refractory ventricular tachycardia (VT) in case series.
Source: Heart Rhythm - Category: Cardiology Authors: Source Type: research
ConclusionSGB increased cSNRT without changing heart rate. CSD was more beneficial for patients with mild ‐to‐moderate heart failure and faster VA.This article is protected by copyright. All rights reserved.
Source: Journal of Cardiovascular Electrophysiology - Category: Cardiology Authors: Tags: ORIGINAL ‐ CLINICAL Source Type: research
Left cardiac sympathetic denervation (LCSD) is as an effective treatment for long QT syndrome, catecholaminergic polymorphic ventricular tachycardia, and in select cases of substrate-mediated ventricular tachycardia (VT) or fibrillation (VF) in ischemic and nonischemic cardiomyopathy. The use and implications of LCSD on pediatric patients with congenital heart disease are not known. Bonura and colleagues (DOI: https://doi.org/10.1016/j.hrcr.2019.04.007) described two pediatric patients that underwent LCSD in the setting of refractory ventricular arrhythmias and congenital heart disease.
Source: Heart Rhythm - Category: Cardiology Authors: Source Type: research
In the evaluation of syncope, history is most important to arrive at a diagnosis.The first step is to confirm whether its truly a syncope or (Metabolic/TIA or seizure. We are easily carried away by the urge to order a Holter monitoring routimely. In reality, the yield is too low (3-5sec Or it may lead to Brady (Pause) dependent escape VT. A pause can be a sinus arrest, Pause or SA block .If pause ends with a junctional escape it becomes a arrest. Look PR interval specifically(A bifasicular block shouldn’t be missed .It can be more dangerous than say a congenital CHB)PR interal represents condcution from SA node to Pu...
Source: Dr.S.Venkatesan MD - Category: Cardiology Authors: Tags: Uncategorized Source Type: blogs
AbstractBackgroundSympathetic neural activation plays a key role in the incidence and maintenance of acute myocardial infarction (AMI) induced ventricular arrhythmia (VA). Furthermore, previous studies showed that AMI might induce microglia and sympathetic activation and that microglial activation might contribute to sympathetic activation. Recently, studies showed that light emitting diode (LED) therapy might attenuate microglial activation. Therefore, we hypothesized that LED therapy might reduce AMI ‐induced VA by attenuating microglia and sympathetic activation.MethodsThirty anesthetized rats were randomly divided in...
Source: Journal of Cardiovascular Electrophysiology - Category: Cardiology Authors: Tags: ORIGINAL ‐ EXPERIMENTAL Source Type: research
Publication date: Available online 23 April 2019Source: Multiple Sclerosis and Related DisordersAuthor(s): Tin Pavičić, Berislav Ruška, Ivan Adamec, Mario HabekAbstractStandard therapy for a relapse of multiple sclerosis is a high dose pulse corticosteroid therapy. Cardiovascular adverse events ranging from palpitations to serious arrhythmias like atrial fibrillation and ventricular tachycardia have been associated with this treatment. The underlying mechanism behind the development of atrial fibrillation and treatment of multiple sclerosis relapse with steroids is still unclear. In this case, a 27-year-old male w...
Source: Multiple Sclerosis and Related Disorders - Category: Neurology Source Type: research
Publication date: April 2019Source: Archives of Cardiovascular Diseases Supplements, Volume 11, Issue 2Author(s): V. Dubes, S. Charron Guitoger, C. Michel, M. Constantin, M. Haissaguerre, M. Hocini, O. Bernus, D. BenoistIntroductionThe right ventricular outflow tract (RVOT) is the main origin of idiopathic ventricular tachycardia (IVTs). Sympathetic stimulation is involved in IVTs but mechanisms underlying this preferential origin remain unknown.ObjectiveTo determine the role of ß1- and ß2-adrenergic receptors (ß1-AR, ß2-AR) in the regional modulation of right ventricular (RV) electrophysiological p...
Source: Archives of Cardiovascular Diseases Supplements - Category: Cardiology Source Type: research
Conclusions: ES management needs a complex assessment and interpretation of a critical situation in a life-threatening condition. Optimal implantable cardioverter-defibrillator-reprogramming, antiarrhythmic drug therapy and sedation are in first-line approach. Catheter ablation is the elective therapy and plays a central key role in the treatment of ES if possible in combination with hemodynamic support.
Source: American Journal of Therapeutics - Category: Drugs & Pharmacology Tags: Systematic Reviews Source Type: research
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