Pulmonary arterial hypertension patients with and without cardiovascular risk factors: results from the ambition trial

Registry data indicate that the demographics of patients with pulmonary arterial hypertension (PAH) have changed over time.1-7 At least in Western countries, the proportion of patients being diagnosed at a more advanced age and/or with more risk factors for left ventricular diastolic dysfunction is increasing.8,9 Clinical outcomes are worse in such patients, relative to their younger counterparts who have fewer risk factors for left ventricular diastolic dysfunction.8,9 These observations have led to some uncertainty in how best to categorise and treat these patients based on the current clinical classification of pulmonary hypertension.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: Original Clinical Science Source Type: research