Application of Trifluoroacetic Acid as a Theranostic Agent for Chemical Ablation of Solid Tissue

ConclusionsTFA was determined to be a theranostic agent for chemical ablation of solid tissue. Ablation was both efficacious and imageable in ex vivo healthy tissue, even at low concentrations or with high temporal resolution.
Source: Journal of Vascular and Interventional Radiology - Category: Radiology Source Type: research

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Authors: Suo F, Zhong B, Lu F, Dong Z Abstract Glioma is the most aggressive brain tumor and is associated with a high mortality rate. The aim of the present study was to explore the association between matrix metalloproteinase 2 (MMP-2) and ephrin type-A receptor 2 (EphA2) expression in glioma cells, and to investigate the contribution of magnetic resonance imaging (MRI) in glioma classification. A total of 43 patients with pathologically confirmed glioma were divided into two groups as follows: Low-grade (grades I and II; n=21) and high-grade (grades IV and IV; n=22). Subsequently, immunohistochemistry staining w...
Source: Oncology Letters - Category: Cancer & Oncology Tags: Oncol Lett Source Type: research
This study aimed to evaluate the success rate and image quality of silent MRI for the brain of children.Materials and MethodsThis was a retrospective study of 3–36-month children who underwent silent or conventional brain MRI at the People's Hospital of Northern Jiangsu from 01/2015 to 02/2018. The success rates were compared. The acoustic noise of each sequence was measured using a decibel meter. The signal-to-noise ratio and contrast-to-noise ratio of the diffusion-weighted imaging, T2W, and T1W sequences were analyzed. Subjective image quality (lesion delineation, visibility, gray-white differentiation, and overal...
Source: Academic Radiology - Category: Radiology Source Type: research
Authors: Yang X, Lu L, Li Q, Huang X, Gong Q, Liu L Abstract The present study aimed to compare the regional homogeneity (ReHo) of resting-state brain function between subjects with strabismic amblyopia and normal controls. A total of 12 adult patients with strabismic amblyopia and 34 age- and gender-matched normal controls were enrolled in the present study. All patients were subjected to resting-state magnetic resonance imaging using a Siemens Trio 3.0T magnetic resonance scanner. ReHo values of the whole brain were calculated and standardized. An independent-samples t-test was used to analyze the differences in ...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
This study mainly investigated altered functional connectivity (FC) of the amygdala in CD patients during resting-state. Magnetic resonance imaging scans were acquired from 42 CD patients and 35 healthy controls (HCs). Whole amygdala bilaterally were selected as regions o f interest (ROIs). Voxel-based morphometry and FC methods were applied to investigate the differences of structure or intrinsic connectivity of the amygdala between the two groups, separately. Pearson correlations were performed to explore relationships between the clinical characteristics and neuro imaging findings in CD patients. Based on the whole...
Source: Brain Imaging and Behavior - Category: Neurology Source Type: research
Conclusion18F-FDG PET proved to be a valuable tool for precise initial staging of pediatric soft-tissue sarcoma patients, especially in detecting lymph node metastasis, and could be included in their initial work-up. Given the relative rarity and heterogeneity of this group of tumors, additional investigations are required to definitely establish a role for18F-FDG PET in the initial staging and therapy planning of soft-tissue sarcoma in the pediatric population.
Source: Pediatric Radiology - Category: Radiology Source Type: research
Conclusion. Postoperative ISI resolution in CSM patients reflects postoperative symptoms and surgical outcomes. Patients who exhibit ISI resolution have better clinical outcomes. Level of Evidence: 3
Source: Spine - Category: Orthopaedics Tags: CERVICAL SPINE Source Type: research
In the past year and a half, various news stories may have led some people to believe that there are blood tests that can diagnose or unmask concussions with a single drop of blood. For individuals who have recently received a bump, hit, or jolt to the head and are wondering if they have sustained a concussion, this may sound like a simple way to find out. Unfortunately, for now it probably isn’t. What do these blood tests actually do? Simply put, these tests measure substances, such as proteins and enzymes, that are released into the blood within hours of a brain injury when there is intracranial damage (including b...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Concussions Memory Neurological conditions Tests and procedures Source Type: blogs
ConclusionsThe study demonstrates that the proposed body-mounted robotic system is able to perform MRI-guided low back injection in a phantom study with sufficient accuracy and with minimal visible image degradation that should not affect the procedure.
Source: International Journal of Computer Assisted Radiology and Surgery - Category: Intensive Care Source Type: research
This study aims at prospectively evaluating an adapted DWI sequence ex vivo and in vivo in oncologic patients undergoing abdominal MRI. Methods This institutional review board–approved, prospective study included phantom measurements, volunteer examinations, and oncologic patient examinations of the abdomen. Fifty-seven MRI examinations in 54 patients (mean age, 58 years; range, 21–90 years) were included into the analysis. The MRI examination were performed at a 1.5 T MRI scanner (MAGNETOM Aera; Siemens Healthcare, Erlangen, Germany) and included both a standard EPI-DWI (s-DWI; b = 50, 900 s/mm2) and an ada...
Source: Investigative Radiology - Category: Radiology Tags: Original Articles Source Type: research
Objectives The aim of this study was to compare a compressed-sensing free-breathing VIBE (fbVIBE) with a conventional breath-hold VIBE (bhVIBE) for dynamic contrast-enhanced imaging of the upper abdomen. Materials and Methods In total, 70 datasets (bhVIBE, n = 30; fbVIBE n = 40; hard-gated [hg] reconstruction, n = 30; motion-state-resolved [mr] reconstruction, n = 10) were assessed by 2 experienced readers. Both sequences were performed on 1.5-T magnetic resonance imaging scanners. The prototypical fbVIBE sequence acquired a navigation signal along with the imaging data and supported 2 different reconstructions: an hg...
Source: Investigative Radiology - Category: Radiology Tags: Original Articles Source Type: research
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