Bioactive ingredients in infant formula: The value for a robust interdisciplinary discussion on safety assessment paradigm
Abrams and Daniels, in a commentary, noted that the recent trend of adding novel ingredients with biological activity to infant formula is not supported by robust scientific literature on their long-term safety or benefits.1 We would like to expand on the authors ’ observations. A review of the current literature shows a widely held presumption that the presence of bioactive constituents in human and other mammalian milks implies anticipated beneficial effects from exposure, and further that this presence, together with traditional toxicologic testing and anthropometric clinical studies, constitutes sufficient evidence to establish their safety for infant formula use at similar levels.
Publication date: Available online 20 November 2019Source: Journal of Advanced ResearchAuthor(s): Sohail Mumtaz, Pradeep Bhartiya, Neha Kaushik, Manish Adhikari, Pradeep Lamichhane, Su-Jae Lee, Nagendra Kumar Kaushik, Eun Ha ChoiAbstractOver the past few decades, microwave (MW) radiation has been widely used, and its biological effects have been extensively investigated. However, the effect of MW radiation on human skin biology is not well understood. We study the effects of pulsed high-power microwaves (HPMs) on melanoma (G361 and SK-Mel-31) and normal human dermal fibroblast (NHDF) cells. A pulsed power generator (Chundo...
Passive measles immunity waned quickly, and most infants were no longer protected from measles by age 3 months, a study found; US experts say the age of vaccination should remain the same.Medscape Medical News
Suresh K. Mukherji
SURESH K. MUKHERJI, MD, MBA, FACR
NEUROIMAGING CLINICS OF NORTH AMERICA
Resting state functional connectivity (RSFC) has been widely studied in functional magnetic resonance imaging (fMRI) and is observed by a significant temporal correlation of spontaneous low-frequency signal fluctuations (SLFs) both within and across hemispheres during rest. Different hypotheses of RSFC include the biophysical origin hypothesis and cognitive origin hypothesis, which show that the role of SLFs and RSFC is still not completely understood. Furthermore, RSFC and age studies have shown an “age-related compensation” phenomenon. RSFC data analysis methods include time domain analysis, seed-based correl...
ConclusionLL/MLD4, MLA, MLD, the degree of luminal diameter stenosis, CCO, RI, and %APV derived from cCTA can support the detection of hemodynamically significant coronary stenosis as compared with iFR®, with LL/MLD4 showing the greatest discriminatory power.