Cleft lip repair: are outcomes between unilateral and bilateral clefts comparable?

This study sought to compare patient demographics, operative course, and peri-operative outcomes between unilateral and bilateral cleft patients. Primary cleft lip repairs were isolated from the National Surgical Quality Improvement Program Pediatric Database (NSQIP-P). Unilateral and bilateral cases of primary cleft lip were identified by ICD codes. Demographics, comorbidities, and post-operative outcomes were compared between cohorts. Patients were propensity matched to control for differences before repeating the analysis. About 4550 cleft lip repairs were evaluated over the 5-year period. Of the cases where the cleft type was identifiable, 75.5% were unilateral clefts and 24.5% were bilateral clefts. The bilateral cleft population had significantly more comorbidities including higher rates of ventilator dependence (1.0% versus 0.4%, p = 0.02), asthma (1.6% versus 0.7%, p = 0.011), tracheostomy (1.6% versus 0.5%, p 
Source: Journal of Plastic Surgery and Hand Surgery - Category: Surgery Tags: J Plast Surg Hand Surg Source Type: research

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ConclusionsOSCS is a rare disorder. Diagnosis can often be challenging because other diseases, such as osteopetrosis, pyknodysostosis, Paget disease of bone, and other sclerosing bone dysplasias, make this difficult to diagnose. Radiologists should be aware of the specific radiographic appearance of this condition to aid in the proper diagnosis and management of these patients.
Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology - Category: ENT & OMF Source Type: research
Since the advent of routine newborn screening programs, neonates at risk for severe combined immunodeficiency (SCID) are often identified before onset of severe illness, which has significantly improved prognosis and outcomes. The differential diagnosis for SCID is broad. This case presents a rare instance of a female infant identified by abnormal newborn screen (NBS) with t-cell lymphopenia that is a result of TP63 mutation (OMIM 603273).
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: M264 Source Type: research
We report a female newborn with abnormal newborn screening (NBS) for severe combined immunodeficiency (SCID)/T cell lymphopenia and chromosome 1q23.3q31.1 deletion. The infant was born at 36-weeks gestation with a birthweight of 1160 grams. At 20-weeks gestation, intrauterine growth retardation, bilateral cleft-lip and cleft-palate, absent kidney, absent stomach bubble, and lateral ventriculomegaly were identified. At birth, she had microcephaly, hypertelorism, bilateral low-set ears with over-folded helices, bilateral complete cleft-lip and cleft-palate, holosystolic murmur and a split second heart sound with a loud P2, s...
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Letter Source Type: research
AbstractTobacco smoke, active or passive exposure was the major cause of preventable morbidity and mortality in the world during twentieth century and will continue to be the same in the twenty-first century also if the current trends continue. Both active and passive smoking are having significance in relation to child health. Exposure starts antenatally from placenta to the fetus and later phases through passive exposure to experimental and regular smoking and ultimately addiction and habitual smoking. Evidences are in favour of causal relationship with intrauterine growth restriction, sudden infant death syndrome, decre...
Source: Indian Journal of Pediatrics - Category: Pediatrics Source Type: research
ConclusionAmong Ontario children who have had TT placement, more than one in four will have multiple sets placed. These identified risk factors permit improved preoperative counseling and enable identification of children who need closer follow‐up. Level of Evidence2b. Laryngoscope, 2017
Source: The Laryngoscope - Category: ENT & OMF Authors: Tags: Pediatrics Source Type: research
Background: The increasing prevalence of smoking among young women are not only associated with long term effects on infants like asthma and cancer but also acute effects like Sudden infant death syndrome and intrauterine death.Objective: To compare the post natal abnormalities and death in infants of smoking and non-smoking womenMethodology: It is cross sectional study in which 100 infants of smoking women were compared with 100 infants of non-smoking women. Study was done in one of the largest tertiary care hospital of Pakistan. Smoking history was evaluated and then both groups were followed up till the delivery. Post n...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: 6.3 Tobacco, Smoking Control and Health Education Source Type: research
Opinion statementChronic urticaria can occur at any age and in both sexes. Regardless of the different populations affected, a stepwise treatment approach is recommended, beginning with non-sedating antihistamines, from licensed doses to a “controlled overdose” up to fourfold, followed by a change to a different antihistamine and/or addition of a leukotriene antagonist if symptoms persist; systemic corticosteroids in short courses (3 to 7 days) can be used for exacerbations. As a third-line therapy in adults, omalizumab is now co nsidered of choice and only in nonresponsive cases to omalizumab cyclosporin ...
Source: Current Treatment Options in Allergy - Category: Allergy & Immunology Source Type: research
Background: Otitis media (OM) refers to bacterial infection or an inflammation of middle ear cleft in younger children than adults. The effusion of fluids in the middle ear or pathological changes in the tympanic membrane or ossicles leads to hearing loss. The aetiopathogenesis of OM is due to the involvement of multiple factors such as demographic, genetic, environmental and other health related factors like infections, allergy, asthma, eustachian tube dysfunction, cleft palate, and adenoid hypertrophy etc., Therefore, the present study aimed to determine the prevalence of OM subtypes and its association with hearing loss...
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Tags: Type: Poster Presentation Source Type: research
We have read with interest the article by Garne et al1 which adds new information on the impact of asthma treatments during pregnancy on the prevalence of congenital malformations. The study concluded that the use of inhaled β2-agonists (short- and long-acting combined) is associated with an increased risk of cleft palate and gastroschisis, whereas the use of inhaled corticosteroids (ICSs) showed no increased risk for any of the examined malformations. We fear however that such a statement could negatively affect the confidence of clinicians and mothers in short-acting β2-agonists (SABAs), specifically salbu...
Source: Journal of Allergy and Clinical Immunology - Category: Allergy & Immunology Authors: Tags: Correspondence Source Type: research
Abstract OBJECTIVE:   To study upper airway breathing in 115 children annually from 8 to 17 years of age with the hypothesis that upper airway respiratory needs increase steadily during growth and show sexual dimorphism. MATERIAL AND METHODS:   To calculate nasal resistance, airflow rate (mL/s) and oronasal pressures (cmH2O) were measured during rest breathing in a seated position using the pressure-flow technique. RESULTS:   Median values of oronasal pressure ranged at different ages in girls from 0.88 to 1.13 and in boys from 0.92 to 1.44 cmH2O, being 0.95 and 0.93 cmH2O at the age of 17...
Source: The Angle Orthodontist - Category: Dentistry Authors: Tags: Angle Orthod Source Type: research
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