A New Echocardiographic Tool for Cardiac Output Evaluation: An Experimental Study

Background: The correlation between cardiac output (CO) evaluated by echocardiography and CO measured by thermodilution (COth) varies according to different studies. A new transthoracic echocardiography (TTE) tool allows automatic calculation of the subaortic velocity time index (VTIauto) and CO (COauto). The main objective was to evaluate the correlation between COth and COauto in an anesthetized, ventilated piglet hemorrhagic shock (HS) model. The secondary objectives were to evaluate the correlation between COth and CO evaluated by manual measurements of VTI, and the preload-dependency of VTIvaresp. Methods: Eighteen piglets were bled until mean arterial pressure reached 40 mm Hg. Controlled hemorrhage was maintained for 30 min before a resuscitation phase. CO was measured by Pulse index Contour Cardiac Output thermodilution methods. At each time of the experiment, three VTI values were measured (min, med, max) and the average value was calculated. COs were calculated by TTE (COmax, COmed, COmin, COave). Results: For the 204 measures attempted, the success rate was 197 (97%) manually and 122 (60%) automatically (P 
Source: Shock - Category: Emergency Medicine Tags: Basic Science Aspects Source Type: research

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Publication date: Available online 14 October 2019Source: Orthopaedics &Traumatology: Surgery &ResearchAuthor(s): Charlotte Crampet, Harold Common, Emma Bajeux, Antoine Bourgoin, Hervé Thomazeau, Jean-Louis Polard, Orthopedics, Traumatology Society of Western FranceAbstractIntroductionAdvances in anesthesia and surgical practices have allowed total hip arthroplasty to be performed as an outpatient procedure. The aim of this study was to demonstrate its feasibility in a selected population compared to a group of inpatients by analyzing the cumulative length of hospital stay, complications and readmissions.Pat...
Source: Orthopaedics and Traumatology: Surgery and Research - Category: Orthopaedics Source Type: research
ConclusionIn this study of pelvic reconstructive surgeries with posterior colporrhaphy and/or perineorrhaphy, there were no differences in pain scores, nor any secondary outcomes, between liposomal bupivacaine and placebo injected into the posterior vaginal compartment.
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
ConclusionWe report continuing positive outcomes and satisfaction with our introduction of Minitouch Endometrial Ablation Procedure as our standard clinical practice. It has provided noticeable improvement in our ablation service from safety and efficacy perspectives. The ability to perform more procedures per session, lowered use of analgesics/anesthetics, and quicker recovery are important benefits in our private hospital setting.
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
ConclusionHysteroscopy as a safe and relatively low pain procedure. Local anesthetic in the form of a paracervical block has been used historically to decrease pain during the procedure. Paracervical block does not significantly decrease pain during procedure, even in menopausal women who were found to have higher pain scales on average. Therefore, future studies should further investigate strategies to decrease pain during office hysteroscopy especially for postmenopausal women.
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
ConclusionWith its flexibility and smaller size over other devices minimizing the need for cervical dilatation and patient discomfort, the use of Minitouch for outpatient treatment of HMB at our center was shown to be well-tolerated, with high reliability of procedure completion, good safety and efficacy outcomes.
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
ConclusionSub-cutaneous and/ or intra-peritoneal anesthesia were not effective in reducing post-operative pain.
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
Publication date: November–December 2019Source: Journal of Minimally Invasive Gynecology, Volume 26, Issue 7, SupplementAuthor(s): J Klebanoff, P Tyan, S Smith, A North, A Sparks, R Amdur, GN MoawadStudy ObjectiveDemonstrate the safety, feasibility, and outcomes associated with the reduced port robotic-assisted hysterectomy (RPRH).DesignWe performed a retrospective cohort study of women undergoing a reduced-port robotic-assisted hysterectomy between 2012 and 2018 for benign indications.SettingA single academic university hospital.Patients or ParticipantsWomen who underwent a reduced port robotic-assisted hysterectomy...
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
ConclusionA four-point TAP block is a safe, efficacious, yet simple procedure which can be performed by the surgeon under laparoscopic visualization.
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
ConclusionSame-day discharge after vaginal hysterectomy with pelvic floor reconstruction appears to be safe and feasible. Patients who were discharged the same-day did not require a higher volume of emergency department or office evaluations.
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
Publication date: Available online 14 October 2019Source: Trends in Pharmacological SciencesAuthor(s): Megan McGrath, Andrea Pence, Douglas E. RainesAll currently available general anesthetics produce potentially deadly side effects. Unfortunately, few approaches have been developed to design safer ones, despite important advances in anesthetic mechanisms research. Cayla and colleagues recently showed that computational methods can be used to identify anesthetic lead compounds devoid of specific side effects.
Source: Trends in Pharmacological Sciences - Category: Drugs & Pharmacology Source Type: research
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