A neonatal pustule:Langerhans cell histiocytosis

We present a case of single lesion self-limited LCH in a full-term male infant with interesting morphology. Physical examination revealed a painless, 6 millimeter, well-demarcated, papule encircled by erythema with central hemorrhage. An infectious workup was negative and a punch biopsy was obtained, which showed a dermal infiltrate of histiocytes consistent with a diagnosis of LCH. The lesion healed without intervention within three weeks. Our case highlights the need for dermatologists to consider LCH in the differential diagnosis for lesions...
Source: Dermatology Online Journal - Category: Dermatology Source Type: research

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Condition:   Langerhans Cell Histiocytosis Intervention:   Drug: Cytarabine Sponsor:   Peking Union Medical College Hospital Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Langerhans Cell Histiocytosis Intervention:   Drug: thalidomide combined with dexamethasone and cyclophosphamide Sponsor:   Peking Union Medical College Hospital Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Shalendra Singh, Shreyas Kate, Rashmi Datta, Virender SuhagIndian Journal of Anaesthesia 2019 63(10):866-868
Source: Indian Journal of Anaesthesia - Category: Anesthesiology Authors: Source Type: research
ConclusionsSP is a common manifestation of PLCH, can be seen in approximately one-fourth of the patients, and has a high recurrence risk. Surgical pleurodesis leads to a substantial reduction in the SP recurrence risk. The risk of an air travel-related SP in patients with PLCH is about 2–3 per thousand flights.Trial registry clinicaltrials.govNCT03052101.
Source: Respiratory Investigation - Category: Respiratory Medicine Source Type: research
Abstract This is a case of a pediatric male who presented with a postauricular mass and pain. Computed tomography and magnetic resonance imaging suggested a diagnosis of Langerhans cell histiocytosis. Characteristic imaging findings and initial workup for Langerhans cell histiocytosis are described. PMID: 31558057 [PubMed - as supplied by publisher]
Source: Ear, Nose and Throat Journal - Category: ENT & OMF Authors: Tags: Ear Nose Throat J Source Type: research
Condition:   Histiocytosis, Langerhans-Cell Interventions:   Other: Biospecimen Collection;   Other: Laboratory Biomarker Analysis;   Other: Questionnaire Administration Sponsors:   Children's Oncology Group;   National Cancer Institute (NCI) Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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