Comparative Antimicrobial Activity of Commercial Wound Care Solutions on Bacterial and Fungal Biofilms

Conclusions Biofilms represent a major clinical challenge, with no clear consensus for treatment of chronic wounds or prosthetic devices. Our results suggest that hypochlorous acid–based wound solutions such as Vashe and PhaseOne are more efficacious than mafenide in eliminating bacterial and fungal biofilms. Further studies are necessary to investigate and compare the in vivo efficacy of these products in clinical care.
Source: Annals of Plastic Surgery - Category: Cosmetic Surgery Tags: Burn Surgery and Research Source Type: research

Related Links:

Argentum Medical’s antimicrobial dressings received an extra bit of validation after strong results from recent lab findings. The Geneva, IL-based company’s Silverlon antimicrobial dressing was found to effectively kill Candida Auris (C. Auris), the emerging “superbug” causing invasive, potentially fatal human infection in more than 30 countries, including the U.S. Argentum Medical commissioned Microbiological Consultants, an independent FDA-registered pharmaceutical testing laboratory, to establish if its metallic wound dressings can destroy C. Auris ...
Source: MDDI - Category: Medical Devices Authors: Tags: Materials Source Type: news
Introduction: Burned patients are at high risk of yeast colonization and thus of invasive fungal infections, particularly to Candida (C.) spp., leading to an increase in morbidity and mortality. While pre-empt...
Source: Annals of Intensive Care - Category: Intensive Care Authors: Tags: Correction Source Type: research
Conclusions These findings of time-related burn wound flora changes along with inappropriate antibiotic prescription led to the development of our institutional syndrome-specific algorithm for the appropriate selection of empiric antimicrobial agents.
Source: Infectious Diseases in Clinical Practice - Category: Infectious Diseases Tags: Original Articles Source Type: research
Publication date: Available online 21 June 2019Source: BurnsAuthor(s): Chathuranga C. De Silva, Nikita Israni, Anand Zanwar, Amit Jagtap, Porakrit Leophairatana, Jeffrey T. Koberstein, Shanta M. ModakAbstractThe delivery of antimicrobial agents to surface wounds has been shown to be of central importance to the wound healing process. In this work, we prepared film forming wound care formulations containing 3 polymers (FTP) that provide broad-spectrum antimicrobial protection for prolonged periods. FTP formulations comprises of a smart gel matrix comprising of pH-degradable and temperature responsive polyacetals (smart poly...
Source: Burns - Category: Dermatology Source Type: research
Conclusion: OFI extracted oil has in vitro antimicrobial/fungal properties and in vivo wound healing activity. It seems to be efficient in the treatment of cutaneous infections and the promoting of the scarring process. PMID: 31097975 [PubMed]
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
Santosh K. Ghosh1*, Thomas S. McCormick1,2 and Aaron Weinberg1* 1Biological Sciences, School of Dental Medicine, Case Western Reserve University, Cleveland, OH, United States 2Dermatology, School of Medicine, Case Western Reserve University, Cleveland, OH, United States Human beta-defensins (hBDs, −1, 2, 3) are a family of epithelial cell derived antimicrobial peptides (AMPs) that protect mucosal membranes from microbial challenges. In addition to their antimicrobial activities, they possess other functions; e.g., cell activation, proliferation, regulation of cytokine/chemokine production, migration, diffe...
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
Gulcin Tezcan1, Ekaterina V. Martynova1, Zarema E. Gilazieva1, Alan McIntyre2, Albert A. Rizvanov1 and Svetlana F. Khaiboullina1,3* 1Institute of Fundamental Medicine and Biology, Kazan Federal University, Kazan, Russia 2Centre for Cancer Sciences, Faculty of Medicine and Health Sciences, University of Nottingham, Nottingham, United Kingdom 3Department of Microbiology and Immunology, University of Nevada, Reno, Reno, NV, United States Inflammation has a crucial role in protection against various pathogens. The inflammasome is an intracellular multiprotein signaling complex that is linked to pathogen sensing and...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
Jin-Yan Wu1,2, Duan-Yong Zhou2, Ying Zhang2, Fei Mi3 and Jianping Xu1,2,4* 1Public Research Laboratory, Hainan Medical University, Haikou, China 2Laboratory for Conservation and Utilization of Bio-Resources and Key Laboratory for Microbial Resources of the Ministry of Education, Yunnan University, Kunming, China 3Research Institute of Nutrition and Food Science, Kunming Medical University, Kunming, China 4Department of Biology, McMaster University, Hamilton, ON, Canada Candida tropicalis is a globally distributed human pathogenic yeast, especially prevalent in tropical and sub-tropical regions. Over the last s...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
Soon-Hwan Oh1, Brooke Smith2, Andrew N. Miller3, Bart Staker4, Christopher Fields5, Alvaro Hernandez5 and Lois L. Hoyer1* 1Department of Pathobiology, University of Illinois at Urbana-Champaign, Urbana, IL, United States 2Department of Biology, Millikin University, Decatur, IL, United States 3Illinois Natural History Survey, Urbana, IL, United States 4Seattle Structural Genomics Center for Infectious Disease, Seattle Children’s Hospital, Seattle, WA, United States 5Roy J. Carver Biotechnology Center, University of Illinois at Urbana-Champaign, Urbana, IL, United States The agglutinin-like sequence (Als)...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
Conclusion Lactobacillus pentosus was the predominant species found at industrial scale in Spanish table olives biofilms, albeit certain genotypes of L. plantarum were also detected. At genotype level, biodiversity was higher in the Spanish-style table olive biofilms than in those of directly brined olives. The multivariate analysis based on technological and probiotic data showed that the main 16 genotypes obtained could be clustered in 3 great phenotypes, with some strains with potential application as multifunctional starters (especially L. pentosus Lp13 and LpG1 genotypes). Data obtained in the present study showed th...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
More News: Burns | Candida | Pathology | Plastic Surgery | Study