The mechanistic actions of different silver species at the surfaces of polyacrylonitrile nanofibers regarding antibacterial activities

Publication date: Available online 16 September 2019Source: Materials Today CommunicationsAuthor(s): Duy-Nam Phan, Nasanjargal Dorjjugder, Yusuke Saito, Goro Taguchi, Hoik Lee, Jung Soon Lee, Ick-Soo KimAbstractThe mechanism of action and toxicity of silver species have been suggested by numerous direct observations. However, as far as we are concerned, comprehensive research to compare modes of action between different silver species at identical silver contents has not yet been reported. The activities of silver species at the interfaces of nanofiber scaffolds and bacterial medium under the impediment of chloride salt, present in antibacterial assays, are very complicated and could bring deeper understanding for research upon antibacterial applications using silver. Here, we prepared silver nitrate, silver zero-valent nanoparticles, and silver mono-valent nanoparticles, incorporated in the nanofiber scaffolds at similar silver contents, then, compared all samples regarding antibacterial effects and fibroblast cytotoxicity. For confirming the success of fabrication, SEM, TEM, EDS, and FT-IR were implemented. Silver nanoparticles were observed to adhere on the nanofibers for Ag2O-PAN 1/20, Ag2O-PAN 1/5, Ag-PAN 1/20, and Ag-PAN 1/5 samples. The XRD spectra exhibited different sets of peaks for zerovalent and monovalent silver nanoparticles, which gave evidence about the nature of silver species incorporated in nanofibers. The XPS data gave an insight into the interactions betw...
Source: Materials Today Communications - Category: Materials Science Source Type: research