Glioma surgery: From preservation of motor skills to conservation of cognitive functions

Publication date: Available online 16 September 2019Source: Journal of Clinical NeuroscienceAuthor(s): Roberto Altieri, Simona Raimondo, Cristiana Tiddia, Diego Sammarco, Fabio Cofano, Pietro Zeppa, Matteo Monticelli, Antonio Melcarne, Carola Junemann, Francesco Zenga, Riccardo Savastano, Diego Garbossa, Francesco Certo, Giuseppe BarbagalloAbstractThe first step of glioma treatment is surgery. Extent of resection (EOR) improves patient survival if surgery does not negatively impair a patient’s neurological status. However, how surgery affects the patient’s quality of life (QOL) has been less studied, especially as regards cognitive aspects. In our study, we retrospectively analyzed our cases with awake surgery. In all patients, surgical excision was stopped when active functions were intraoperatively identified. A neuropsychological assessment was performed both before and after surgery (5 days and 1 month after). Writing, motor speech, comprehension, expression, reading, pragmatics, attention, memory, problem solving and visuoperceptive functions were evaluated and scored with the NOMS scale. We found no differences in the median values of writing and motor speech, while there was a difference in the following variables: comprehension, expression, reading, pragmatics, attention, memory, problem solving and visuoperceptive functions. Moreover, the Dunn test did not show any difference between preoperative evaluation and evaluation performed 30 days after surgery reg...
Source: Journal of Clinical Neuroscience - Category: Neuroscience Source Type: research