Long noncoding RNA TTN-AS1 enhances the malignant characteristics of osteosarcoma by acting as a competing endogenous RNA on microRNA-376a thereby upregulating dickkopf-1.

In conclusion, TTN-AS1 functions as a competing endogenous RNA targeting miR-376a and increases the malignancy of OS cells in vitro and in vivo by upregulating DKK1.
PMID: 31525734 [PubMed - as supplied by publisher]

Source: Aging - September 15, 2019 Category: Biomedical Science Authors: Li S, Liu F, Pei Y, Wang W, Zheng K, Zhang X Tags: Aging (Albany NY) Source Type: research