Dorsal Root Ganglion Stimulation in Experimental Painful Diabetic Polyneuropathy: Delayed Wash ‐Out of Pain Relief After Low‐Frequency (1Hz) Stimulation

ConclusionsThese results show that DRGS is equally effective when applied at low ‐, mid‐, and high‐frequency in an animal model of PDPN. However, low‐frequency‐(1 Hz)‐DRGS resulted in a delayed wash‐out effect, which suggests that this is the most optimal frequency for pain therapy in PDPN as compared to mid‐ and high‐frequency.

Source: Neuromodulation: Technology at the Neural Interface - September 15, 2019 Category: Biotechnology Authors: Eva Koetsier, Glenn Franken, Jacques Debets, Sander M.J. Kuijk, Bengt Linderoth, Elbert A. Joosten, Paolo Maino Tags: Basic Research Source Type: research