Mitochondrial dysfunction is associated with long-term cognitive impairment in an animal sepsis model

Conclusion:Long-term impairment of brain function is temporally related to mitochondrial dysfunction. Activators of autophagy and mitochondrial biogenesis could rescue animals from cognitive impairment.

Source: Clinical Science - September 15, 2019 Category: Biomedical Science Authors: Manfredini, A., Constantino, L., Pinto, M. C., Michels, M., Burger, H., Kist, L. W., Silva, M. C., Gomes, L. M., Dominguini, D., Steckert, A., Simioni, C., Bogo, M., Streck, E., Barichello, T., de Quevedo, J., Singer, M., Ritter, C., Dal-Pizzol, F. Tags: PublishAheadOfPrint Source Type: research