A Randomized Trial on Platelet Rich Plasma Versus Saline Dressing of Diabetic Foot Ulcers

Condition:   Diabetic Foot Interventions:   Drug: PRP gel;   Drug: Saline dressing Sponsor:   Mansoura University Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials

Related Links:

Abstract The species Kalanchoe laciniata (L.) DC. and Bryophyllum pinnatum (Lam) Pers. are native from Brazil and Madagascar, respectively. Both belonging to the Crassulaceae family and being widely used by population as a natural anti-inflammatory agent. These species have similar leaf morphology and for this reason, they are known by the same popular name as “ sai ão ” or “ coirama ” . Several studies have been published involving different parts and preparations of these species. Therefore, this review aims to provide an update overview about the traditional uses, chemical constitution, ph...
Source: Revista Brasileira de Farmacognosia - Category: Drugs & Pharmacology Source Type: research
ConclusionNeedle flexor tenotomies are a relatively safe and effective treatment compared to tenotomies done by scalpel, both as treatment for ulcers and to prevent formation of new ulcers associated with hammer, mallet and claw toe deformities. As a side note, transfer complications are avoidable if all toes on one or both feet are tenotomized in one procedure.
Source: Journal of Clinical and Translational Endocrinology - Category: Endocrinology Source Type: research
Peripheral arterial disease (PAD) is a highly prevalent, yet underdiagnosed, condition [1]. Although frequently asymptomatic, it is a leading cause of leg pain, claudication, ulceration, gangrene, and even amputation. On the other hand, patients with type 2 diabetes (T2DM) are more likely to develop PAD than do the non-diabetic subjects. Furthermore, they are affected by more severe and extensive form of the disease that tends to involve more distal arteries, progress more quickly, and also it is more likely to lead to ischemic ulceration and amputation [2].
Source: Primary Care Diabetes - Category: Primary Care Authors: Tags: Original research Source Type: research
Publication date: Available online 9 October 2019Source: Journal of Herbal MedicineAuthor(s): Lokesh K Mishra, Dipayan Sarkar, Rao Mentreddy, Kalidas ShettyAbstractBasil (Ocimum spp.) is an important herb from the Lamiaceae family with a long history of use in traditional medicine and food applications. Thus, targeting basil varieties for developing herbal medicines against non-communicable chronic diseases (NCDs) such as type 2 diabetes has significant merit. The aim of this study was to screen Asian basil varieties with therapeutic potential for type 2 diabetes targeting relevant phenolic bioactive-linked antioxidant, an...
Source: Journal of Herbal Medicine - Category: Complementary Medicine Source Type: research
Source: Infection and Drug Resistance - Category: Infectious Diseases Tags: Infection and Drug Resistance Source Type: research
In this study, there was a high prevalence of the EMRSA-15 clone presenting multiple resistances in diabetic foot ulcers making these infections complicated to treat leading to a higher morbidity and mortality in diabetic patients.
Source: European Journal of Clinical Microbiology and Infectious Diseases - Category: Microbiology Source Type: research
We describe and analyse the features of rat bites in 2 patients with diabetic neuropathic feet and highlight 8 clinical features that should raise suspicion and alert the clinician to this possibility.
Source: The American Journal of Medicine - Category: General Medicine Authors: Tags: Brief Observation Source Type: research
uml; Ç Abstract BACKGROUND: Recent studies showed no reduction in major amputation rates after introduction of a multidisciplinary team (MDT) approach for the treatment of diabetic foot ulcer. The efficacy of MDTs in the current standard of care is being questioned. This retrospective single-center study evaluated the efficacy of an outpatient MDT approach on limb salvage and ulcer healing in treating diabetic foot ulcers. METHODS: Patients with a diabetic foot ulcer treated before (2015) and after (2017) implementation of an MDT in a single center were compared. The MDT met weekly and consisted of a v...
Source: The Journal of Cardiovascular Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Tags: J Cardiovasc Surg (Torino) Source Type: research
AbstractIntroductionDiabetic foot ulcers develop with deviations in the distribution of plantar pressure. It is difficult to interpret any alteration in plantar pressure under different conditions of type 2 diabetes mellitus (T2DM). The aim of this study was to gain a better insight into the variations in plantar pressure with increased duration of diabetes.MethodsPlantar pressure was examined in 1196 participants with or without T2DM. Subjects with normal glucose tolerance (NGT) and impaired glucose tolerance (IGT) were assigned to control groups, and those with T2DM were divided into five groups according to diabetes dur...
Source: Diabetes Therapy - Category: Endocrinology Source Type: research
Conditions:   Diabetic Foot Ulcer;   Peripheral Neuropathy;   Treatment Adherence and Compliance Intervention:   Device: External shoe lift Sponsor:   Universidad Complutense de Madrid Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
More News: Diabetes | Diabetic Ulcers | Endocrinology | Research