HbA1c versus oral glucose tolerance test as a method to diagnose diabetes mellitus in vascular surgery patients

Conclusions: Compared with the OGTT the HbA1c cut-off value of >= 48 mmol/mol (6.5%) had a 45.5% sensitivity to diagnose DM in patients with peripheral arterial disease. OGTT and HbA1c categorized different individuals with DM and intermediate hyperglycaemia. The total prevalence of pathologic glucose metabolism was substantially higher based on HbA1c values than based on OGTT. The high prevalence of DM and intermediate hyperglycaemia when using HbA1c in this study may reflect a high chronic glycaemic burden in patients with peripheral arterial disease. Further studies on vascular surgery patients are needed to identify which method, OGTT or HbA1c, is the better in predicting DM and future clinical development of vascular disease.Trial registration: REK vest 14109
Source: Cardiovascular Diabetology - Category: Cardiology Authors: Source Type: research