Antibody responses against the vaccine antigens Ov -103 and Ov -RAL-2 are associated with protective immunity to Onchocerca volvulus infection in both mice and humans

Conclusions/SignificanceAlum-adjuvantedOv-103 andOv-RAL-2 vaccines have the potential of reducing infection and thus morbidity associated with onchocerciasis also in humans. The development of cytophilic antibodies, that function in antibody-dependent cellular cytotoxicity, is essential for a successful prophylactic vaccine against this infection.

http://feeds.plos.org/~r/plosntds/NewArticles/~3/_enEOZKaJVg/article

Source: PLoS Neglected Tropical Diseases - September 15, 2019 Category: Tropical Medicine Authors: Jovvian George P. Source Type: research

More News: Parasitic Diseases | Parasitology | River Blindness | Tropical Medicine | Vaccines

Antibody responses against the vaccine antigens < i > Ov < /i > -103 and < i > Ov < /i > -RAL-2 are associated with protective immunity to < i > Onchocerca volvulus < /i > infection in both mice and humans