Diagnostic rescue of a silent scalp swelling by fine-needle aspiration
Smita Chandra, Manveer Kour Raina, Sushil Kumar Shukla, Anuradha Kusum, Vipul NautiyalCytoJournal 2019 16(1):19-19
Authors: Li H, Zhao J, Zhang J, Wang C, Li M, Wu S, Su Z, Pan Q Abstract A total of 15-30% of thyroid nodules that are evaluated by fine-needle aspiration are not clearly determined to be benign or malignant. Gene mutation analysis is recommended for the evaluation of thyroid nodules using clinical guidelines. The detection of circulating tumor DNA (ctDNA) has the potential to aid in the screening, diagnosis and prediction of thyroid cancer prognosis, and can be used when tissues are difficult to obtain. In the present study, whole-exome sequencing (WES) was performed on tumors and matched normal tissues from 10 pa...
AbstractEndoscopic ultrasonography (EUS) is a modality with high spatial resolution that enables comprehensive observation of the entire pancreas and plays an important role in the diagnosis of pancreatic lesions. Recent advances in diagnostic imaging methods such as ultrasound, computed tomography, and magnetic resonance imaging have increased the incidental detection of pancreatic cystic lesions (PCLs). EUS has been recognized as an essential diagnostic method for the detection and evaluation of PCLs. EUS has two important roles: as a detailed (high-resolution) imaging diagnostic method and as an approach for collecting ...
Endoscopy DOI: 10.1055/a-1011-3796 © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents | Full text
A new test that looks for a chemical fingerprint of thyroid cancer in fine needle aspiration samples may improve the accuracy of preoperative diagnosis.
Conclusion: The EUS and FNA are good tools to confirm malignancy and rule out benign treatable conditions like TB for any patient with a pancreatic mass suspicious for carcinoma. PMID: 31588486 [PubMed - in process]
This study investigates the feasibility of using US-FNA samples for both cytological diagnosis and whole transcriptome RNA-sequencing analysis (RNA-Seq), with the ultimate aim of improving canine prostate cancer management.The feasibility of the US-FNA procedure was evaluated intra vitam on 43 dogs. Additionally, aspirates from 31 euthanised dogs were collected for standardising the procedure. Each aspirate was separated into two subsamples: for cytology and RNA extraction. Additional prostate tissue samples served as control for RNA quantity and quality evaluation, and differential expression analysis. The US-FNA sampling...
Condition: Lung Carcinoma Interventions: Procedure: Bronchoscopy; Procedure: Ultrasound-Guided Transbronchial Needle Aspiration Sponsors: Ohio State University Comprehensive Cancer Center; National Cancer Institute (NCI) Not yet recruiting
Biopsy instruments are being developed to enhance the diagnostic yield of endobronchial ultrasound (EBUS) sampling. Convex linear probe EBUS is a modality that has been refined and become the primary approach for tissue acquisition, particularly for target lesions in the mediastinum and pulmonary hila. Using this technology, EBUS guided transbronchial needle aspiration (TBNA) has been shown to have high sensitivity and specificity in diagnosing small cell and non-small cell lung carcinomatosis, whether it be lymph node metastases or primary lesional material [1 –4].
Standard suction and slow-pull techniques have been utilized during endoscopic ultrasound-guided fine needle aspiration of pancreatic solid lesions, but the correct sampling technique remains unclear. New needles designed to obtain samples suitable for histological evaluation have become available. We performed a study comparing the two sampling methods during endoscopic ultrasound-guided fine needle biopsy (EUS-FNB) in patients with pancreatic solid lesions.
Conclusions: The needle G is an independent factor associated with successful NGS. This finding may suggest that the quantity of cells obtained from EUS-TA specimens is important for successful NGS. PMID: 31581388 [PubMed - as supplied by publisher]