Obesity linked to significant increased risk of developing type 2 diabetes

Research presented at the Annual Meeting of the European Association for the Study of Diabetes in Barcelona has linked obesity to a nearly 6-fold increased risk of developing type 2 diabetes, and proves the most dominant risk factor over others such as genetics and lifestyle.Medical Xpress
Source: Society for Endocrinology - Category: Endocrinology Source Type: news

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The evidence is clear. Bariatric surgery provides wide-ranging benefits to adolescents with obesity and type 2 diabetes, says Dr Louise Baur.Medscape Diabetes &Endocrinology
Source: Medscape Diabetes Headlines - Category: Endocrinology Tags: Diabetes & Endocrinology Commentary Source Type: news
Conditions:   Obesity;   Diabetes Mellitus, Type 2;   Insulin Resistance Intervention:   Other: Methylation status Sponsor:   University of Arizona Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Childhood Obesity Intervention:   Behavioral: Evaluation of whiteboard videos Sponsors:   The Hospital for Sick Children;   University of Ottawa Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
The Metabolic Syndrome may be tentatively defined as the clustering of several metabolic risk factors in the same individual. A progressively higher number of children and adolescents is affected by this syndrome worldwide, mainly as a consequence of the constant increase of the prevalence of obesity and sedentary habits. As obesity, the chance that the metabolic syndrome traks into adulthood is high. Moreover, the evidence of an association between the duration of the exposition to metabolic risk factors and morbidity and mortality justifies early treatment and prevention of the metabolic syndrome in both children and ado...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Source Type: research
ConclusionStudies on arthroplasty survival should systematically mention gender and diabetes status and beware of potential group incomparability.Level of evidenceIII, cohort study.
Source: Orthopaedics and Traumatology: Surgery and Research - Category: Orthopaedics Source Type: research
ConclusionUrinalysis screening followed by evaluation of risk factors is a simple and efficient way to identify children with diabetes in schools.
Source: Journal of the Formosan Medical Association - Category: General Medicine Source Type: research
FRIDAY, Oct. 11, 2019 -- Poor glycemic control is associated with increased risks for stroke and death among patients with type 2 diabetes, according to a study published online Oct. 1 in Diabetes, Obesity and Metabolism. Alexander Zabala, M.D.,...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
Albiflorin (AF) is a small molecule (MW 481) isolated from Paeoniae radix, a plant used as a remedy for various conditions with pathogenesis shared by metabolic diseases. Reported here is our characterization of its therapeutic profiles in three mouse models with distinctive pathological features of metabolic syndrome (MetS). Our results firstly showed that AF alleviated high fat (HF) induced obesity and associated glucose intolerance, suggesting its therapeutic efficacy for MetS. In the type 2 diabetes (T2D) model induced by a combination of HF and low doses of streptozotocin, AF lowered hyperglycaemia and improved insuli...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
ConclusionThese results indicate that enhanced brain insulin signaling transduction and brain glucose utilization play important roles in the antidiabetic effect of DJB.
Source: Obesity Surgery - Category: Surgery Source Type: research
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