Do preoperative anxiety and depression influence the outcome of knee arthroplasty?

Publication date: Available online 14 September 2019Source: Reumatología Clínica (English Edition)Author(s): Manuel Jiménez Ortiz, Alfonso Espinosa Ruiz, Cristóbal Martínez Delgado, Pablo Barrena Sánchez, José A. Salido ValleAbstractBackgroundThe association of depression and chronic pain in knee osteoarthritis is a complex and difficult phenomenon to understand. In fact, establishing the order of appearance of these entities might result in an arduous task.ObjectiveIn addition to analysing the relationship between preoperative anxiety and depression according to the results of total knee arthroplasty (TKA), we will assess the evolution of anxiety and depression symptoms.Material and methodsA study of 260 patients with a mean age of 70.8 years. Patients were evaluated preoperatively and one year post-surgery completing the Knee Society Score (KSS), the Visual Analogue Scale (VAS), the Hospital Anxiety and Depression Scale (HADS) for the assessment of anxiety and depression, and the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) for quality of life.ResultsThe mean scores of preoperative depression and anxiety decreased postoperatively from 6.55/7.63 to 4.96/5.96, respectively, a reduction that was statistically significant (P 
Source: Reumatologia Clinica - Category: Rheumatology Source Type: research

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I was looking back over the last 8 years since the first Wheat Belly book was released. It’s been 8 years of astounding, truly breathtaking stories of success over weight issues, health, and physical transformations that skeptics even today claim are impossible. It’s been a virtual avalanche of wonderful stories. Although I’ve seen all of them, often more than once, I could not help but be overcome with satisfaction and pride for the many, many spectacular photos and stories people have shared. So I thought it would be fun to re-post a small sample of some of these stories dating back from the start of th...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: Wheat Belly Success Stories grain-free Inflammation Source Type: blogs
Conclusions: Study results suggest multiple mechanisms contributing to pain experiences in IBD, to include central mechanisms. Features related to demographics, extraintestinal manifestations, IBD subtype, and clinical IBD features were not predictors of subgroup membership. However, total comorbidity demonstrated association with pain subgroups in this population.
Source: The Clinical Journal of Pain - Category: Anesthesiology Tags: Original Articles Source Type: research
In this study, we evaluated the involvement of sigma-1 receptor (σ1R) on the nociceptive, cognitive and emotional alterations associated with chronic osteoarthritis pain. Monosodium iodoacetate (MIA) was injected into the knee of Swiss-albino CD1 mice to induce osteoarthritis pain, which then received a repeated treatment with the σ1R antagonist E-52862 or its vehicle. Nociceptive responses and motor performance were assessed with the von Frey and the Catwalk gait tests. Cognitive alterations were evaluated using the novel object recognition task, anxiety-like behaviour with the elevated plus maze and the zero-...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
Conclusion: These findings support the hypothesis that in FM a deteriorated function of cortical inhibition, indexed by a higher SICI parameter, a lower function of the DPMS, together with a higher level of BDNF indicate that FM has different pathological substrates from depression. They suggest that an up-regulation phenomenon of intracortical inhibitory networks associated with a disruption of the DPMS function occurs in FM. Introduction Major depressive disorder (MDD) and fibromyalgia (FM) present overlapped symptoms. Although the connection between these two disorders has not been elucidated yet, the disruption...
Source: Frontiers in Human Neuroscience - Category: Neuroscience Source Type: research
Publication date: Available online 18 April 2019Source: Journal of Sport and Health ScienceAuthor(s): Xin Luan, Xiangyang Tian, Haixin Zhang, Rui Huang, Na Li, Peijie Chen, Ru WangAbstractA growing understanding of the benefits of exercise over the past few decades has prompted researchers to take an interest in the possibilities of exercise therapy. Because each sport has its own set of characteristics and physiological complications that tend to appear during exercise training, the effects and underlying mechanisms of exercise remain unclear. Thus, the first step in probing exercise effects on different diseases is the s...
Source: Journal of Sport and Health Science - Category: Sports Medicine Source Type: research
This study had a large sample size and obtained positive findings in both patients’ subjective ratings and in inflammatory marker levels. It demonstrates the benefits of adding Tai Chi to an antidepressant regimen but does not examine the specific effect of Tai Chi on depression.Field et al. (16) investigated the effects of combined Tai Chi/yoga in 92 prenatally depressed pregnant women. They found that women practicing Tai Chi/yoga (20 min per week for 12 weeks) had lower depression, anxiety, and sleep disturbance scores compared to a waitlist control group (Table 1). This study had a large sample size and provided ...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
Treating chronic low back pain (CLBP) with spine-focused interventions is common, potentially dangerous, and often ineffective. We posit that CLBP in older adults is a geriatric syndrome – a final common pathway for the expression of multiple contributors. We have published evidence and expert consensus-based algorithms to guide evaluation and treatment of key biopsychosocial CLBP contributors in older adults – hip osteoarthritis, myofascial pain, fibromyalgia, sacroiliac joint syndrome, lumbar spinal stenosis, leg length inequality, lateral hip/thigh pain, anxiety, depression, insomnia, and maladaptive coping....
Source: The Journal of Pain - Category: Materials Science Authors: Source Type: research
Anxiety and depression are associated with increased pain responses in chronic pain states. The extent to which anxiety drives chronic pain, or vice versa, remains an important question that has implications for analgesic treatment strategies. Here, the effect of existing anxiety on future osteoarthritis (OA) pain was investigated, and potential mechanisms were studied in an animal model. Pressure pain detection thresholds, anxiety, and depression were assessed in people with (n = 130) or without (n = 100) painful knee OA. Separately, knee pain and anxiety scores were also measured twice over 12 months in 4730 individuals ...
Source: Pain - Category: Anesthesiology Tags: Research Paper Source Type: research
Authors: Harth M, Nielson WR Abstract INTRODUCTION: Most arthritides are associated with pain and psychological distress (clinically significant depression and anxiety). Pain and depression are mutually exacerbating; both may continue even when joint involvement appears well controlled. Area covered: There is strong evidence that arthritis-related stress impacts the central nervous system and, together with peripheral inflammatory changes, can cause central sensitization that can lead to chronic pain and worsening of affective distress. Cytokines and chemokines participate both in joint inflammation and in central ...
Source: Expert Review of Clinical Immunology - Category: Allergy & Immunology Tags: Expert Rev Clin Immunol Source Type: research
DiscussionThe results will investigate the influence of celecoxib treatment on cerebral activity of patients with KOA and the possible relationship between the cerebral activity changes and improvement of clinical variables so as to explore the central mechanism of celecoxib in treating knee pain.Trial registrationChiCTR-IOR-17012365. Registered on August 14, 2017.
Source: Trials - Category: Research Source Type: clinical trials
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