Sleep duration and architecture during ASV for central sleep apnoea in systolic heart failure

ConclusionsDisturbances of sympatho-vagal balance during ASV might help explain increased mortality during ASV. Since sympathetic tone is highest in REM-sleep and vagal predominance occurs during N3 sleep, these findings generate new hypotheses for the increased mortality seen in SERVE-HF.
Source: Respiratory Physiology and Neurobiology - Category: Respiratory Medicine Source Type: research