Design of a liquid crystal-based aptasensing platform for ultrasensitive detection of tetracycline.

We describe the optimized condition for maintaining the homeotropic orientation of LCs, which are suitable for the tetracycline detection. The average gray-scale intensities of polarizing optical microscopy images were calculated to quantitatively detect tetracycline concentrations. The aptasensor works especially at trace level of tetracycline as low as 0.5 pM. Moreover, the LC aptasensor was successfully used to detect tetracycline in the real milk sample. According to the results, the proposed LC aptasensor for tetracycline detection is simple, ultra-sensitive, label free and ease of preparation.
PMID: 31514901 [PubMed - in process]

Source: Talanta - September 15, 2019 Category: Chemistry Authors: Rouhbakhsh Z, Verdian A, Rajabzadeh G Tags: Talanta Source Type: research