Natural polysaccharides with immunomodulatory activities.

Natural polysaccharides with immunomodulatory activities.
Mini Rev Med Chem. 2019 Sep 13;:
Authors: Zhao Y, Yan B, Wang Z, Li M, Zhao W
Abstract
Natural polysaccharides can be extracted from plants, fungi, algae, animals, and bacteria. The monosaccharide compositions and glucosidic bonds of polysaccharides from different origins vary substantially. Natural polysaccharides have been shown to possess a variety of biological activities including antitumor, anticoagulant, antioxidative, antiviral, immunomodulatory, antihyperlipidemic and antihepatotoxic activities. Their properties are mainly due to their structure characteristics. The present paper will review the mechanisms of the immunomodulatory activities of natural polysaccharides. In particular, it will provide an overview on representative natural polysaccharide immunomodulators. Additionally, the structure-activity relationship of these activities will be discussed.
PMID: 31518223 [PubMed - as supplied by publisher]

Source: Mini Reviews in Medicinal Chemistry - September 12, 2019 Category: Chemistry Authors: Zhao Y, Yan B, Wang Z, Li M, Zhao W Tags: Mini Rev Med Chem Source Type: research