Sensors, Vol. 19, Pages 3985: Design and Development of Photonic Biosensors for Swine Viral Diseases Detection

Sensors, Vol. 19, Pages 3985: Design and Development of Photonic Biosensors for Swine Viral Diseases Detection Sensors doi: 10.3390/s19183985 Authors: Amadeu Griol Sergio Peransi Manuel Rodrigo Juan Hurtado Laurent Bellieres Teodora Ivanova David Zurita Carles Sánchez Sara Recuero Alejandro Hernández Santiago Simón Gyula Balka Ioannis Bossis Alessandro Capo Alessandra Camarca Sabato D’Auria Antonio Varriale Alessandro Giusti In this paper we introduce a field diagnostic device based on the combination of advanced bio-sensing and photonics technologies, to tackle emerging and endemic viruses causing swine epidemics, and consequently significant economic damage in farms. The device is based on the use of microring resonators fabricated in silicon nitride with CMOS compatible techniques. In the paper, the designed and fabricated photonic integrated circuit (PIC) sensors are presented and characterized, showing an optimized performance in terms of optical losses (30 dB per ring) and extinction ration for ring resonances (15 dB). Furthermore, the results of an experiment for porcine circovirus 2 (PCV2) detection by using the developed biosensors are presented. Positive detection for different virus concentrations has been obtained. The device is currently under development in the framework of the EU Commission co-funded project SWINOSTICS.
Source: Sensors - Category: Biotechnology Authors: Tags: Article Source Type: research